Comparison of Contrast-Enhanced Computed Tomography with Positron Emission Tomography-Computed Tomography in Assessing Extra-Nodal Involvement in Lymphoma

Sana Ahmed  Khan; Rizwan  Bilal; Atiq Ur Rehman  Slehria; Mobeen  Shafique; Shaista  Nayyar; Hafsa  Sadiq

doi:10.51253/pafmj.v75i4.9164

Authors

Sana Ahmed Khan Department of Radiology, Armed Forces Institute of Radiology & Imaging, Rawalpindi/National University of Medical Sciences (NUMS) Pakistan
Rizwan Bilal Department of Radiology, Armed Forces Institute of Radiology & Imaging, Rawalpindi/National University of Medical Sciences (NUMS) Pakistan
Atiq Ur Rehman Slehria Department of Radiology, Armed Forces Institute of Radiology & Imaging, Rawalpindi/National University of Medical Sciences (NUMS) Pakistan
Mobeen Shafique Department of Radiology, Combined Military Hospital, Pano Aqil/National University of Medical Sciences (NUMS) Pakistan
Shaista Nayyar Department of Radiology, Pakistan Air Force Hospital, Islamabad Pakistan
Hafsa Sadiq Department of Radiology, Armed Forces Institute of Radiology & Imaging, Rawalpindi/National University of Medical Sciences (NUMS) Pakistan

DOI:

https://doi.org/10.51253/pafmj.v75i4.9164

Keywords:

CECT, Extra nodal, Lymphoma, PET-CT

Abstract

Objective: To compare the sites of extra-nodal involvement by Contrast-Enhanced Computed Tomography (CECT) and Positron Emission Tomography-Computed Tomography (PET-CT) in lymphoma patients

Study Design: Cross-sectional study

Place and Duration of Study: Armed Forces Institute of Radiology & Imaging, Military Hospital, Rawalpindi Pakistan, from Aug to Dec 2021.

Methodology: A total of 216 patients were included in the study who were diagnosed with lymphoma and presented with suspicion of extra-nodal metastasis. CECT and PET CT were performed in these patients, and a comparison of CECT and PET CT was made in the detection of sites of extra-nodal involvement.

Results: A total of 216 patients were included in the study, and the ability of CECT and PET CT was compared to detect the sites of extra-nodal involvement. The sensitivity, specificity, PPV, and NPV for 18-FDG PET-CT were calculated as 92.7%, 100.0%, 100.0% and 95.7% respectively, which was significantly more than CECT.

Conclusion: PET CT has proven to be a superior diagnostic tool for identifying sites of extra-nodal involvement as compared to CECT. It plays a significant role in guiding effective disease management.

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