Association of ABO and RH Blood Groups with Gestational Diabetes Mellitus in Patients Attending a Tertiary Care Hospital of Lahore, Pakistan

Authors

  • Sajida Shaheen Department of Pathology, Combined Military Hospital Lahore/National University of Medical Sciences (NUMS) Pakistan
  • Muhammad Abdul Naeem Department of Pathology, Combined Military Hospital Lahore/National University of Medical Sciences (NUMS) Pakistan
  • Muhammad Farooq Department of Dental, Combined Military Hospital Nowshera/National University of Medical Sciences (NUMS) Pakistan
  • Muhammad Tariq Khan Department of Pathology, Combined Military Hospital Lahore/National University of Medical Sciences (NUMS) Pakistan
  • Viqar Ashraf Department of Pathology, Combined Military Hospital Lahore/National University of Medical Sciences (NUMS) Pakistan
  • Amena Arif Department of Pathology, Combined Military Hospital Lahore/National University of Medical Sciences (NUMS) Pakistan

DOI:

https://doi.org/10.51253/pafmj.v73i6.9083

Keywords:

ABO and Rh blood groups, Gestational diabetes mellitus, Normal glucose tolerance

Abstract

Objective: To find out any association of ABO and Rh blood groups with gestational diabetes mellitus (GDM).

Study Design: Comparative cross-sectional study.

Place and Duration of Study: Pathology and Gynecology departments of Combined Military Hospital-Lahore from Jun to Sep 2020.

Methodology: A total of 250 patients of GDM and 250 pregnant ladies with normal glucose tolerance (NGT) were included in the study. The Oral glucose tolerance test (OGTT) was performed with a 75g glucose load, and results were interpreted
according to the American Diabetes Association 2020 criteria. Blood glucose samples were taken in sodium fluoride containers in fasting conditions, 1 hour and 2 hours post-glucose load. Samples for blood groups were obtained in plain and EDTA containers. Blood glucose samples were analyzed using the Hexokinase method's automated chemistry analyzer, Cobas c-501. ABO and RhD blood grouping were carried out by forward and reverse techniques in the blood bank of CMH Lahore.

Results: A total of 250 (50%) pregnant ladies with OGTT suggestive of Gestational Diabetes Mellitus and 250 (50%) pregnant ladies with OGTT suggestive of Normal Glucose Tolerance (NGT) were included in the study. No statistically significant difference was observed with ABO and RhD blood groups among them (p=0.944).

Conclusion: There is no significant association found between ABO and RhD blood groups with Gestational Diabetes
Mellitus.

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Published

28-12-2023

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Original Articles

How to Cite

1.
Shaheen S, Abdul Naeem M, Farooq M, Tariq Khan M, Ashraf V, Arif A. Association of ABO and RH Blood Groups with Gestational Diabetes Mellitus in Patients Attending a Tertiary Care Hospital of Lahore, Pakistan. Pak Armed Forces Med J [Internet]. 2023 Dec. 28 [cited 2024 Jul. 25];73(6):1817-20. Available from: https://pafmj.org/PAFMJ/article/view/9083