Psoriasis and Risk of Migraines in Patients Reporting to a Tertiary Care Setup in Pakistan: A Cross-Sectional Study

Abstract

Objective: To look for migraine headaches and associated factors in patients being managed for psoriasis at a tertiary
healthcare setup in Rawalpindi, Pakistan.

Study Design: Comparative cross-sectional study.

Place and Duration of Study: Department of Dermatology, Pak Emirates Military Hospital, Rawalpindi Pakistan, from Mar
2021 to Feb 2022.

Methodology: One hundred and forty patients of psoriasis being managed at our Dermatology Unit were included in the
analysis. All patients were screened with the Migraine Screen Questionnaire (MS-Q), and those having scores equal to or more than four were evaluated by medical specialists, and diagnosis of migraine was established based on the International
Classification of Headache Disorders diagnostic criteria for migraine. An association of relevant risk factors was established
with migraine among these patients.

Results: Out of 140 patients with psoriasis, 75(53.4%) were male, while 65(46.6%) were female. Eighty-five (60.7%) patients
had migraine confirmed by clinical criteria, while 55(39.3%) had no migraine. Statistical analysis revealed that more body
surface area involvement and longer duration of psoriasis had a statistically significant relationship with migraine among the study participants (p-value <0.05).

Conclusion: The study showed that patients with psoriasis had an approximately 3-fold increased risk of migraine headaches compared to the normal population. Most of the patients had migraine without aura. Patients with longer duration of psoriasis and those with more surface area of the body affected with psoriasis were at an increased risk of migraines compared to other patients.