HUMAN IMMUNODEFICIENCY VIRUS (HIV): A DIAGNOSTIC DILEMMA

Muhammad Ali Rathore; Saifullah Khan Niazi; Mommana Ali Rathore; Muhammad Sajid Yazdani

doi:10.51253/pafmj.v72iSUPPL-2.9000

Authors

Muhammad Ali Rathore Armed Forces Institute of Transfusion/National University of Medical Sciences (NUMS) Rawalpindi Pakistan
Saifullah Khan Niazi Armed Forces Institute of Pathology/National University of Medical Sciences (NUMS) Rawalpindi Pakistan
Mommana Ali Rathore Army Medical College/National University of Medical Sciences (NUMS) Rawalpindi Pakistan
Muhammad Sajid Yazdani Armed Forces Institute of Transfusion/National University of Medical Sciences (NUMS) Rawalpindi Pakistan

DOI:

https://doi.org/10.51253/pafmj.v72iSUPPL-2.9000

Keywords:

False positive, Human immunodeficiency virus, Laboratory Diagnosis

Abstract

Human immunodeficiency virus is a blood borne virus and is being routinely screened in the blood banks since 1983. The sensitivity and specificity of HIV tests have improved dramatically over the years, but even then, false positive results do occur, which need confirmatory testing. A young male who arrived at Armed Forces Institute of Transfusion (AFIT), Rawalpindi, for blood donation, was repeatedly “positive” on serological assays. Nucleic acid amplification test (NAT) was performed which gave a “Negative” result. Line immunoassay (LIA) was performed to solve the discrepancy in test results.