Early Complications of Surfactant Administration In Neonates

Hafiz zulqar nain; Muhammad Tariq  Nadeem; Sammar  Hussain; Ali  Mujtaba; Saeed  Zaman; Waleed  Ali

doi:10.51253/pafmj.v74i3.8675

Authors

Hafiz zulqar nain Department of Pediatrics, Pak Emirates Military Hospital /National University of Medical Sciences (NUMS) Rawalpindi Pakistan
Muhammad Tariq Nadeem Department of Pediatrics, Pak Emirates Military Hospital /National University of Medical Sciences (NUMS) Rawalpindi Pakistan
Sammar Hussain Department of Pediatrics, Pak Emirates Military Hospital /National University of Medical Sciences (NUMS) Rawalpindi Pakistan
Ali Mujtaba Department of Pediatrics, Combined Military Hospital Zhob /National University of Medical Sciences (NUMS) Pakistan
Saeed Zaman Department of Pediatrics, Pak Emirates Military Hospital /National University of Medical Sciences (NUMS) Rawalpindi Pakistan
Waleed Ali Department of Pediatrics, Pak Emirates Military Hospital /National University of Medical Sciences (NUMS) Rawalpindi Pakistan

DOI:

https://doi.org/10.51253/pafmj.v74i3.8675

Keywords:

Bradycardia, Complications, Neonates, Surfactant, Pulmonary hemorrhage

Abstract

Objective: To assess the early complications of surfactant administration in neonates with respiratory distress syndrome.

Study Design: Perspective longitudinal study.

Place and Duration of Study: Pak Emirates Military Hospital (PEMH), Rawalpindi Pakistan, from Jun to Dec 2021.

Methodology: A total of 64 neonates admitted in ICU with gestational age 27-32 weeks requiring Continuous Positive Airway Pressure and surfactant administration were included. Neonatal complications after 24 hours of administration of surfactant and final outcome was recorded on a predesigned data collection tool.

Results: Mean duration of stay on ventilator was 41.12±8.88 hours. Mean duration for Continuous Positive Airway Pressure was 43.59±22.70 hours. Second dose of surfactant was given to 34(53.1%) of neonates. Among neonates 25% suffered from pulmonary hemorrhage and 7.8% from bradycardia, 48(75%) were discharged and 16(25%) died.

Conclusion: The mortality rate decreased in neonates after administration of surfactant. In future, we will implement surfactant in term neonates, diagnosed with Respiratory Distress Syndrome, in order to improve the survival of neonates and reduce complications.

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