Comparison of Neonatal Outcome of Late Pre-Term Neonates Associated with and Without Intrauterine Growth Retardation
DOI:
https://doi.org/10.51253/pafmj.v73i6.8605Keywords:
Intrauterine growth retardation, Neonates, Outcome, Pre-termAbstract
Objective: To compare the neonatal outcome of late pre-term neonates with and without intrauterine growth retardation at a nursing intensive care unit of our hospital
Study Design: Comparative cross-sectional study.
Place and Duration of Study: Pak Emirates Military Hospital ,Rawalpindi Pakistan, from Jun 2021 to Jan 2022.
Methodology: Patients were divided into two groups for comparison, late pre-term neonates with and without intrauterine
growth retardation. Intrauterine growth retardation was assessed via ultrasound examination at >29 and <34 weeks of
gestation. Neonatal outcome parameters were compared in neonates with and without intrauterine growth retardation.
Results: A total of 110 neonates were included in the final analysis. Of them, 69(62.7%) were male, while 41(37.3%) were
females. Patients were divided into two groups for the sake of comparison. Fifty-eight (52.7%) had no intrauterine growth
retardation, while 52(47.3%) had intrauterine growth retardation. Statistical analysis revealed that longer duration of
admission, hypoglycemia and hyperbilirubinemia were found statistically significantly more in late pre-term neonates who
had intrauterine growth retardation as compared to those who did not have intrauterine growth retardation (p-value<0.05).
Conclusion: Intrauterine growth retardation was a commonly observed finding among neonates who were born at late preterm. Neonates with intrauterine growth retardation were more at risk of certain complications like long stay at the neonatal intensive care unit, hypoglycemia and hyperbilirubinemia
Downloads
Metrics
References
Al-Wassia H, Saber M. Admission of term infants to the neonatal
intensive care unit in a Saudi tertiary teaching hospital:
cumulative incidence and risk factors. Ann Saudi Med 2017;
(6): 420‐424. https://doi.org/10.5144/0256-4947.2017.420
Quddusi AI, Razzaq A, Hussain S, Hussain A. Pattern of
neonatal admission at the Children's Hospital and the Institute of
Child Health, Multan. J Ayub Med Coll Abbottabad 2012; 24(2):
‐110
Chow S, Chow R, Popovic M. A Selected Review of the Mortality
Rates of Neonatal Intensive Care Units. Front Public Health 2015;
(1): 225. https://doi.org/10.3389%2Ffpubh.2015.00225
Fisher AL, Sangkhae V, Presicce P, Chougnet CA, Jobe AH,
Kallapur SG, et al. Fetal and amniotic fluid iron homeostasis in
healthy and complicated murine, macaque, and human
pregnancy. JCI Insight 2020; 5(4): e135321.
https://doi.org/10.1172/jci.insight.135321
Salman M, Rathore H, Arif S, Ali R, Khan AA, Nasir M, et al.
Frequency of Immediate Neonatal Complications (Hypoglycemia and Neonatal Jaundice) in Late Preterm and Term
Neonates. Cureus 2021; 13(1): e12512.
Neonatal Outcome of Late Pre-Term Neonates Associated
Pak Armed Forces Med J 2023; 73(6): 1710
https://doi.org/10.7759/cureus.12512
Khowaja WH, Leghari AL, Hussain AS, Ariff S, Khan IA.
Frequency and Early Complications of Late Preterm Infants: A
Descriptive Analysis from Two Secondary-care Hospitals of
Karachi. Cureus 2019; 11(9): e5789.
https://doi.org/10.7759/cureus.5789.
Sharma D, Shastri S, Sharma P. Intrauterine Growth Restriction:
Antenatal and Postnatal Aspects. Clin Med Insights Pediatr 2016;
(3): 67-83. https://doi.org/10.4137/CMPed.S40070
Colella M, Frérot A, Novais ARB, Baud O. Neonatal and LongTerm Consequences of Fetal Growth Restriction. Curr Pediatr
Rev 2018; 14(4): 212-218.
https://doi.org/10.2174/1573396314666180712114531
Ortigosa Rocha C, Bittar RE, Zugaib M. Neonatal outcomes of
late-preterm birth associated or not with intrauterine growth
restriction. Obstet Gynecol Int 2010; 2010(1): 231842.
https://doi.org/10.1155/2010/231842
Haroon A, Ali SR, Ahmed S, Maheen H. Short-term neonatal
outcome in late preterm vs. term infants. J Coll Phys Surg Pak
; 24(1): 34-38.
Ortigosa Rocha C, Bittar RE, Zugaib M. Neonatal outcomes of
late-preterm birth associated or not with intrauterine growth
restriction. Obstet Gynecol Int 2010; 2010(3): 231842.
https://doi.org/10.1155/2010/231842
Chew LC, Verma RP. Fetal Growth Restriction. Treasure Island
(FL): StatPearls Publishing; 2021, Available at:
https://www.ncbi.nlm.nih.gov/books/NBK562268/
Karnati S, Kollikonda S, Abu-Shaweesh J. Late preterm infants -
Changing trends and continuing challenges. Int J Pediatr Adolesc
Med 2020; 7(1): 36-44.
https://doi.org/10.1016%2Fj.ijpam.2020.02.006
Karataşlı V, Kanmaz AG, İnan AH, Budak A, Beyan E. Maternal
and neonatal outcomes of adolescent pregnancy. J Gynecol
Obstet Hum Reprod 2019; 48(5): 347-350.
https://doi.org/10.1016/j.jogoh.2019.02.011
Mallick AK, Venkatnarayan K, Thapar RK, Tewari VV, Shaw SC.
Morbidity Patterns of Late Preterm Babies Born Small for
Gestation. Indian J Pediatr 2019; 86(7): 578-583.
https://doi.org/10.1007/s12098-019-02925-4
Kc A, Wrammert J, Nelin V, Ewald U, Clark R, Målqvist M, et al.
Level of mortality risk for babies born preterm or with a small
weight for gestation in a tertiary hospital of Nepal. BMC Public
Health 2015; 15(2): 877.
https://doi.org/10.1186/s12889-015-2232-1
Acmaz G, Ozdemir F, Sahin E, Sahin ME, Madendag Y, Demir
TB, et al. Adverse fetal outcomes in patients with IUGR are
related with fetal diaphragm evaluation parameters. Paediatr
Respir Rev 2021; 37(3): 48-53.
https://doi.org/10.1016/j.prrv.2020.07.005
Kreko E, Kola E, Sadikaj F, Dardha B, Tushe E. Neonatal
Morbidity in Late Preterm Infants Associated with Intrauterine
Growth Restriction. Open Access Maced J Med Sci 2019; 7(21):
Downloads
Published
How to Cite
Issue
Section
