Correlation of Body Mass Index with Inflammatory Markers in Rheumatoid Arthritis Patients


  • Yusra Tayyab Department of Biochemistry, Army Medical College/National University of Medical Sciences (NUMS) Rawalpindi Pakistan
  • Amir Rashid Department of Biochemistry, Army Medical College/National University of Medical Sciences (NUMS) Rawalpindi Pakistan
  • Muhammad Javad Yousaf Department of Biochemistry, Army Medical College/National University of Medical Sciences (NUMS) Rawalpindi Pakistan
  • Adnan Manzar Department of Medicine, Pak Emirates Military Hospital/National University of Medical Sciences (NUMS) Rawalpindi Pakistan
  • Asifa Majeed Department of Biochemistry, Army Medical College/National University of Medical Sciences (NUMS) Rawalpindi Pakistan



Body mass index (BMI), Erythrocyte sedimentation Rate (ESR), C reactive protein (CRP), Rheumatoid arthritis


Objective: To study the correlation of body mass index with inflammatory markers among rheumatoid arthritis patients.

Study Design: Comparative cross-sectional study.

Place and Duration of Study: Department of Biochemistry and Molecular Biology, Army Medical College, Rawalpindi
Pakistan, in collaboration with the Rheumatology Department and laboratory of Pak Arab Emirates Military Hospital
(PEMH), Rawalpindi Pakistan from Jan 2020 to Jan 2021.

Methodology: The study sample was sixty in number and was divided into two groups. Diagnosed Rheumatoid Arthritis (RA) patients on modifying rheumatic Drugs (DMARDs) therapy constituted Group-I. At the same time, Group-II consisted of 30 healthy individuals. BMI, C reactive proteins (CRP) and erythrocyte sedimentation rate (ESR) of both groups were assessed and compared. The correlation of BMI with inflammatory markers was also assessed in both groups.

Results: Sixty subjects with a mean age of 44.90±10 years were distributed evenly among two groups. Mean inflammatory
markers for ESR and CRP, were 30.70±16.46 and 11.65±12.97, respectively, of Group-I. There was a significant difference in
CRP and ESR (p ≤ 0.05) among the two groups. The mean BMI was 25.20±4.65, which was also raised for Group-I. BMI was
positively correlated with inflammatory markers in both groups. Group-I showed a more positive correlation of BMI with ESR (r=0.23) than Group-II (r= 0.143).

Conclusion: BMI is positively correlated with inflammatory status among RA patients.


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How to Cite

Tayyab, Y., Amir Rashid, Muhammad Javad Yousaf, Adnan Manzar, & Asifa Majeed. (2023). Correlation of Body Mass Index with Inflammatory Markers in Rheumatoid Arthritis Patients. Pakistan Armed Forces Medical Journal, 73(6), 1753–1756.



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