Comparative Study Between Permethrin-5% and Oral Ivermectin for the Treatment of Scabies
DOI:
https://doi.org/10.51253/pafmj.v74i3.8563Keywords:
Ivermectin, Permethrin, ScabiesAbstract
Objective: To compare the efficacy of 5% Permethrin with the oral Ivermectin for management of scabies.
Study Design: Quasi-experimental Study.
Place and Duration of Study: Department of Dermatology, CMH, Abbottabad Pakistan, from Jun to Nov 2021.
Methodology: Our study enrolled 100 patients, aged 5-80 years, after informed consent. Demographic information and study variables were noted in a data collection tool. All participants were randomly assigned to one of two groups i.e. Group A received Permethrin 5% twice with a one-week interval, whereas Group B received a single dose of oral Ivermectin. The evaluation was conducted at 2-4 week intervals.
Results: From our sample of 100 participants, 57 were females and 43 were males; age ranged from 5 to 80 years. Group A of Permethrin-5% 43(86%) patients’ symptoms improved than in Group B 24(48%) patients of oral Ivermectin. There was also a statistically significant relationship between Permethrin and Ivermectin (p-value<0.001).
Conclusions: Permethrin is more effective than Ivermectin as first dose response. Permethrin is more compliant and safer for scabies patients.
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Copyright (c) 2024 Naheed Khan, Majid Hussain, Bushra Muzaffar, Adeel Siddique, Rizwan Ali Khan, Tamoor Nazir
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