Relationship Between Vitamin D Deficiencyand Risk of Gdm In Pregnant Women
DOI:
https://doi.org/10.51253/pafmj.v75iSUPPL-6.8517Keywords:
Glucose intolerance, Oral glucose tolerance test (OGTT), Vitamin D deficiency.Abstract
Objective: To determine the association between vitamin D status (normal vs deficient) with the risk of Gestational diabetes mellitus among pregnant females of Pakistan.
Study Design: Prospective comparative study.
Place and Duration of Study: Liaquat National Hospital Karachi from April 2021 to April 2022.
Methodology: After approval from Ethical Review Board, total of 120 pregnant patients fulfilling inclusion and exclusion criteria were enrolled in this study. All women had their OGTT performed at mid pregnancy. On the basis of vitamin D levels patients were categorized into Vitamin D sufficient (> 30 ng/ml), insufficient (21-29 ng/ml) and deficient (< 20 ng/ml) group.60 women with vitamin D sufficient level were included in control group , while 60 women with vitamin D insufficient and deficient level were included in study group.
Results: On comparison in control group, Gestational diabetes mellitus found in 18(30 %) cases. In study group, 3(16.7%) cases among vitamin D insufficient while 24(57.1%) cases among vitamin D deficient level had Gestational diabetes mellitus (p-value =0.003).
Conclusion: Our observations showed a significant increased risk of gestation diabetes mellitus with vitamin D deficiency as compared to vitamin D sufficient (> 30 ng/ml) and insufficient level (<20ng/ml) in Pakistani pregnant women.
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