CORRELATION OF ANGIOGRAPHIC FINDINGS AND SYNTAX SCORE WITH HIGH SENSITIVITY TROFON IN PATIENTS PRESENTING WITH NON ST ELEVATION MYOCARDIAL INFARCTION

Abstract

Objective: This study was done to find out how angiographic findings including severity, site, type of lesion, calcification and based on these findings the Syntax Score were related to the level of cardiac Troponin-I (cTn-I) in patients of Non ST Elevation Myocardial Infarction.

Study Design: Cross sectional study. Place and Duration of Study: Armed forces institute of Cardiology/National Institute of Health Sciences Rawalpindi Pakistan, from July 2016 to Dec 2016.

Material and Methods: A total of 120 patients were studied over a period of 6 months. They were divided into two groups according to High sensitivity Trop I levels; high/Group A (Troponin-I level >0.78ng/ml) and low Group B (Troponin-I 0.06–0.78 ng/ml). Thus 54 patients fell into Group A while 66 into Group B. The angiographic characteristics and Syntax Score of the two groups of patients were then compared.

Results: A total of 120 patients were studied. There were 86 (71.6%) males and 34 (28.3%) females with age range 29-77 years. cTnI was markedly raised in 59 (49%) patients i.e. Group A and lower in 61 (51%) i.e. Group B. High levels of cnT-I were related to number of vessels involved p<0.001. Three vessel involvement was higher 34 (57%) of Group A in comparison with group B 4 (6.5%). While more patients had single vessel involvement in Group B vs Group A i.e. 38 (62%) and 5(8.4%). Type A lesions were more common in Group A than Group B; 44(72%) vs 11(18%). Thrombus burden was higher in Group A, Calcification frequency was more in Group A than B; 73% vs 11% p<0.001 and Syntax Score was >32 in 52% of Group A and in 3% of Group B p<0.05. Proximal lesions were more frequent in Group A 33(55%) than Group B 26(42%) but the correlation was insignificant p=0.48.

Conclusion: Patients of Non-ST elevation Myocardial Infarctionwith raised serum Troponin-I had more severe coronary disease and higher Syntax Score than those with lower serum Troponin-I.