Relationship of GallstoneDisease with Age and Gender

Faheem; Zakaullah Khan; Muhammad Yousaf Shah; Muhammad Nafe Bin Tahir; Rohan Qamar; Saba Yousaf

doi:10.51253/pafmj.v74i4.8460

Authors

Faheem Department of Surgery, Combined Military Hospital/National University of Medical Sciences (NUMS) Rawalpindi Pakistan
Zakaullah Khan Department of Surgery, Combined Military Hospital/National University of Medical Sciences (NUMS) Rawalpindi Pakistan
Muhammad Yousaf Shah Department of Surgery, Combined Military Hospital/National University of Medical Sciences (NUMS) Rawalpindi Pakistan
Muhammad Nafe Bin Tahir Department of Surgery, Combined Military Hospital/National University of Medical Sciences (NUMS) Rawalpindi Pakistan
Rohan Qamar Department of Surgery, Combined Military Hospital/National University of Medical Sciences (NUMS) Rawalpindi Pakistan
Saba Yousaf Lahore University of Management Sciences

DOI:

https://doi.org/10.51253/pafmj.v74i4.8460

Keywords:

Cholecystitis, Gallstones, Laparoscopic Cholecystectomy

Abstract

Objective: To analyze the role of age and gender in gallstones formation and their relation to the types of stones formed.

Study Design: Cross-sectional study.

Place and Duration of Study: Combined Military Hospital, Rawalpindi Pakistan, from Jan 2019 to Jun 2021.

Methodology: Laparoscopic cholecystectomies were performed on 400 patients with symptomatic gallstones and acute cholecystitis. Variables such as gender, number of pregnancies if female, age, stone-types, and fatty liver.

Results: The study included 166(41.5%) male and 234(58.5%) female patients. The mean age was 48.89±16.3 years. 106(63.9%) male patients had cholesterol stones while 32(19.3%) and 28(16.9%) had bilirubin and mixed stones, respectively. Among female patients, 182(77.8%) had cholesterol stones, 26 (11.1%) had mixed and 26(11.1%) had bilirubin stones. Patients with gall stones in age groups <25 years, 26-50 years, 51-75 years and greater than 76 years were 35(8.8%), 186(46.5%), 144(36%) and 35(8.8%) respectively. The frequency of cholesterol gallstones was 14(40%), 130(69.9%), 127(88.2%) and 17(48.6%) in all the four age groups, respectively. The relationship of cholesterol gallstones with fatty liver and number of pregnancies was positive with coefficients β=6.61 for fatty liver and β=5.9 for number of pregnancies.

Conclusion: The gender and age of patients had significant relationship with gallstones. The frequency of cholesterol stones positively relates to fatty liver and number of pregnancies in females.

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