Role of Vitamin D Supplementation in Prevention of Recurrent Benign Paroxysmal Positional Vertigo

Authors

  • Muhammad Sarfraz Department of ENT, Combined Military Hospital/National University of Medical Sciences (NUMS) Rawalpindi Pakistan
  • Muhammad Ali Hashmi Department of ENT, Combined Military Hospital/National University of Medical Sciences (NUMS) Rawalpindi Pakistan
  • Abdul Hakim Department of ENT, Combined Military Hospital/National University of Medical Sciences (NUMS) Rawalpindi Pakistan
  • Kashif Obaid Niazi Department of ENT, Combined Military Hospital/National University of Medical Sciences (NUMS) Rawalpindi Pakistan
  • Kamran Zamurrad Malik Department of ENT, Combined Military Hospital/National University of Medical Sciences (NUMS) Rawalpindi Pakistan
  • Shakeel Ahmed Department of ENT, Combined Military Hospital/National University of Medical Sciences (NUMS) Rawalpindi Pakistan

DOI:

https://doi.org/10.51253/pafmj.v74i3.8397

Keywords:

Benign Paroxysmal Positional Vertigo, Nystagmus, Recurrence, Vitamin D Deficiency.

Abstract

Objective: to determine of vitamin D administration in preventing recurring benign paroxysmal positional vertigo events.

Study Design: Quasi experimental study.

Place and Duration of Study: Department of ENT, Combined Military Hospital, Rawalpindi Pakistan, from Jul 2021 to Jan 2022.

Methodology: Study was conducted on 80 patients who were diagnosed with recurrent benign paroxysmal vertigo. Patients were enrolled in two groups (Group A and B) by lottery method. Vitamin D supplements and canal repositioning manoeuvre were administered to patients in Group A, while just canal repositioning procedure was given to patients in Group B. Patients were told to follow up over six months. Vitamin D supplement consumption and BPPV attacks were tracked over 6-month follow up period.

Results: In follow-up period, most patients in Group A 24(60.0%) had no episodes of vertigo, whereas 10(25.0%) had single episode of vertigo. Furthermore, none of the patients experienced three episodes. Many patients in Group B 19(47.5%) developed one or more episodes. The difference between both groups was statistically significant (p<0.05).

Conclusion: Low vitamin D levels are found in most individuals with benign paroxysmal positional vertigo events. Vitamin D supplementation significantly decreased the frequency and recurrence of benign paroxysmal positional vertigo events, according to the findings.

Downloads

Download data is not yet available.

References

Jeong SH, Kim JS, Kim HJ, Choi JY, Koo JW, Choi KD et al. Prevention of benign paroxysmal positional vertigo with vitamin D supplementation: A randomized trial. Neurology 2020; 95(9): e1117-e1125

https://doi.org/10.1212/WNL.0000000000010343

Zhu CT, Zhao XQ, Ju Y, Wang Y, Chen MM, Cui Y. Clinical Characteristics and Risk Factors for the Recurrence of Benign Paroxysmal Positional Vertigo. Front Neurol 2019; 10: 1190. https://doi.org/10.3389/fneur.2019.01190

Wu Y, Fan Z, Jin H, Guan Q, Zhou M, Lu X, et al. Assessment of Bone Metabolism in Male Patients with Benign Paroxysmal Positional Vertigo. Front Neurol 2018; 9: 742.

https://doi.org/10.3389/fneur.2018.00742

Yang CJ, Kim Y, Lee HS, Park HJ. Bone mineral density and serum 25-hydroxyvitamin D in patients with idiopathic benign paroxysmal positional vertigo. J Vestib Res 2018; 27(5-6): 287-294 https://doi.org/10.3233/VES-170625

Yang H, Gu H, Sun W, Li Y, Wu H, Burnee M, et al. Estradiol deficiency is a risk factor for idiopathic benign paroxysmal positional vertigo in postmenopausal female patients. Laryngoscope 2018; 128(4): 948-953.

https://doi.org/10.1002/lary.26628

Han W, Fan Z, Zhou M, Guo X, Yan W, Lu X, et al. Low 25-hydroxyvitamin D levels in postmenopausal female patients with benign paroxysmal positional vertigo. Acta Otolaryngol 2018; 138(5): 443-446

https://doi.org/10.1080/00016489.2017.1416168

Ding J, Liu L, Kong WK, Chen XB, Liu X. Serum levels of 25-hydroxy vitamin D correlate with idiopathic benign paroxysmal positional vertigo. Biosci Rep 2019; 39(4): BSR20190142. https://doi.org/10.1042/BSR20190142

Luryi AL, Lawrence J, Bojrab DI, LaRouere M, Babu S, Zappia J et al. Recurrence in Benign Paroxysmal Positional Vertigo: A Large, Single-Institution Study. Otol Neurotol 2018; 39(5): 622-627 https://doi.org/10.1097/MAO.0000000000001800

Yang B, Lu Y, Xing D, Zhong W, Tang Q, Liu J, et al. Association between serum vitamin D levels and benign paroxysmal positional vertigo: a systematic review and meta-analysis of observational studies. Eur Arch Otorhinolaryngol 2020; 277(1): 169-177. https://doi.org/10.1007/s00405-019-05694-0

Arshad M, Abbas S, Qureshi IA. Delay in diagnosis and treatment of benign paroxysmal positional vertigo in current practice. J Ayub Med Coll Abbottabad 2013; 25(1-2): 93-95.

Giacomini PG, Ferraro S, Di Girolamo S, Villanova I, Ottaviani F. Benign paroxysmal positional vertigo after intense physical activity: a report of nine cases. Eur Arch Otorhinolaryngol 2009; 266s (11): 1831-1835. https://doi.org/10.1007/s00405-009-0938-3

Thacher TD, Clarke BL. Vitamin D insufficiency. Mayo Clin Proc 2011; 86(1): 50-60. https://doi.org/10.4065/mcp.2010.0567

Rhim GI. Serum Vitamin D and Long-term Outcomes of Benign Paroxysmal Positional Vertigo. Clin Exp Otorhinolaryngol 2019; 12(3): 273-278 https://doi.org/10.21053/ceo.2018.00381

Mithal A, Wahl DA, Bonjour JP, Burckhardt P, Dawson-Hughes B, Eisman JA, et al. IOF Committee of Scientific Advisors (CSA) Nutrition Working Group. Global vitamin D status and determinants of hypovitaminosis D. Osteoporos Int 2009; 20(11): 1807-1820.

https://doi.org/10.1007/s00198-009-0954-6

Buki B, Ecker M, Junger H, Lundberg YW. Vitamin D deficiency and benign paroxysmal positioning vertigo. Med Hypotheses 2013; 80(2): 201–204.

Yu S, Liu F, Cheng Z, Wang Q. Association between osteo-porosis and benign paroxysmal positional vertigo: A systematic review. BMC Neurol 2014; 14(1): 110.

Mohsin FD, Alharbawi FA, Alraho ST. Benign paroxysmal positional vertigo and vitamin D deficiency. Pharma Innov J 2019; 8(3): 49–52.

Jeong SH. Decreased serum vitamin D in idiopathic benign paroxysmal positional vertigo. J Neurol 2013; 260(3): 832–838.

Xiang G, Dong F, Gu J. Analysis of effect of 1α-hydroxyvitamin D3 on benign paroxysmal positional vertigo and risk factors. Exp Ther Med 2018; 15(3): 2321-2326.

https://doi.org/10.3892/etm.2018.5699

Yamanaka T. Osteoporosis as a risk factor for the recurrence of benign paroxysmal positional vertigo. Laryngoscope 2013; 123(11): 2813–2816.

Talaat HS. Reduction of recurrence rate of benign paroxysmal positional vertigo by treatment of severe vitamin D deficiency. Auris Nasus Larynx 2016; 43(3): 237–241.

Abdelmaksoud AA, Fahim DFM, Bazeed SES. Relation between vitamin D deficiency and benign paroxysmal positional vertigo. Sci Rep 2021; 11: 16855.

https://doi.org/10.1038/s41598-021-96445-x

Downloads

Published

28-06-2024

Issue

Section

Original Articles

How to Cite

1.
Sarfraz M, Ali Hashmi M, Hakim A, Niazi KO, Malik KZ, Ahmed S. Role of Vitamin D Supplementation in Prevention of Recurrent Benign Paroxysmal Positional Vertigo. Pak Armed Forces Med J [Internet]. 2024 Jun. 28 [cited 2024 Dec. 25];74(3):754-7. Available from: https://pafmj.org/PAFMJ/article/view/8397