Autoimmune Polyglandular Syndrome Type-2 A Case Report on a Rare Disease

Wahaj Ul Hassan; Ummarah Zafar Farid; Kamran Ali; Umer Naseer

doi:10.51253/pafmj.v73i6.8277

Authors

Wahaj Ul Hassan Department of Medicine, Combined Military Hospital, Malir/National University of Medical Sciences (NUMS) Pakistan
Ummarah Zafar Farid Department of Medicine, Combined Military Hospital, Malir/National University of Medical Sciences (NUMS) Pakistan
Kamran Ali Department of Medicine, Combined Military Hospital, Quetta/National University of Medical Sciences (NUMS) Pakistan
Umer Naseer Department of Medicine, Combined Military Hospital, Peshawar/ National University of Medical Sciences (NUMS) Pakistan

DOI:

https://doi.org/10.51253/pafmj.v73i6.8277

Keywords:

Autoimmune polyglandular syndrome, Addison's disease, Myasthenia gravis

Abstract

Autoimmune polyglandular syndromes (APS) are rare disorders involving multiple endocrine and non-endocrine organs.
These are often difficult to diagnose, as the clinical presentation of these is insidious. We present a case where a 29-year-old man presented to the Emergency Department in a state of altered sensorium with a history of focal seizures. His clinical
presentation further included hypotension, malaise, and diplopia. A detailed workup revealed multiple endocrine gland
involvement, and a diagnosis of APS was made.

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