In Hospital Outcome of COVID-19 Patients with Acute Myocardial Infarction
DOI:
https://doi.org/10.51253/pafmj.v74i2.7953Keywords:
COVID-19, Co-morbid, Myocardial infarction, MortalityAbstract
Objective: To determine the hospital outcome of acute myocardial infarction patients with COVID-19 and compare it with
patients without COVID-19.
Study Design: Comparative cross-sectional study.
Place and Duration of Study: Armed Forces Institute of Cardiology and National Institute of Heart Diseases, Rawalpindi
Pakistan, from Mar to Oct 2021.
Methodology: The study included PCR-positive patients with COVID-19 infection who had acute myocardial infarction
diagnosed by a consultant cardiologist. The hospital recorded clinical outcomes within two days of acute myocardial
infarction. Data regarding outcome was compared with patients who had acute myocardial infarction but did not have
COVID-19.
Results: Fifty cases of COVID-19 and myocardial infarction were included in the study. An equal number of patients with no
evidence of COVID-19 but having myocardial infarction were also included. The mean age of the study participants was
49.96±897 years. Out of 100 patients, 79(79%) were male, while 21(21%) were female. Statistical analysis showed that all the
outcome parameters studied had no significant difference in both the acute myocardial infarction patients with and without
COVID-19 (p-value>0.05).
Conclusion: Our study results revealed no statistically significant difference in the hospital outcome of patients with acute
myocardial infarction who were suffering from COVID-19 and those who were not.
Downloads
References
Beh DLL, Ng DHL, Ong SWX, Sutjipto S, Lee PH, Oon J, et al. The
Pandemic Academy: Reflections of Infectious Diseases Fellows
During COVID-19. Open Forum Infect Dis 2020; 7(7): ofaa256
https://doi.org/10.1093/ofid/ofaa256
Qureshi M, Khan T, Mohsin S, Zahid M, Ashraf M, Channa A, et
al. The price of Battling COVID-19: A cross sectional survey. Pak
Armed Forces Med J 2020;COVID-19(2): S468-473.
El Aidaoui K, Haoudar A, Khalis M, Kantri A, Ziati J, El Ghanmi
A, et al. Predictors of Severity in Covid-19 Patients in Casablanca,
Morocco. Cureus 2020; 12(9): e10716.
https://doi.org/10.7759/cureus.10716
Mechanic OJ, Gavin M, Grossman SA. Acute Myocardial
Infarction. In: StatPearls Treasure Island (FL): StatPearls
Publishing; 2021.
Ibanez B, James S, Agewall S, Antunes MJ, Bucciarelli-Ducci C,
Bueno H, et al ESC Scientific Document Group. 2017 ESC
Guidelines for the management of acute myocardial infarction in
patients presenting with ST-segment elevation: The Task Force for
the management of acute myocardial infarction in patients
presenting with ST-segment elevation of the European Society of
Cardiology (ESC). Eur Heart J 2018; 39(2): 119-177.
https://doi.org/10.1093/eurheartj/ehx393
Pina A, Castelletti S. COVID-19 and Cardiovascular Disease: a
Global Perspective. Curr Cardiol Rep 2021; 23(10): 135.
https://doi.org/10.1007/s11886-021-01566-4
Gluckman TJ, Wilson MA, Chiu ST, Penny BW, Chepuri VB,
Waggoner JW, et al. Case Rates, Treatment Approaches, and
Outcomes in Acute Myocardial Infarction During the
Coronavirus Disease 2019 Pandemic. JAMA Cardiol 2020; 5(12):
-1424. https://doi.org/10.1001/jamacardio.2020.3629
Primessnig U, Pieske BM, Sherif M. Increased mortality and
worse cardiac outcome of acute myocardial infarction during the
early COVID-19 pandemic. ESC Heart Fail 2021; 8(1): 333-343.
https://doi.org/10.1002/ehf2.13075
Tamimi HA, Alhamad Y, Khazaal F, ElHassan M, ALBinali H,
Arabi A et al. The Outcome of COVID-19 Patients with Acute
Myocardial Infarction. medRxiv 2020; 7(21): 20156349.
https://doi.org/10.1101/2020.07.21.20156349
Mengal N, Saghir T, Hassan Rizvi SN, Khan N, Qamar N,
Masood S, et al. Acute ST-Elevation Myocardial Infarction Before
and During the COVID-19 Pandemic: What is the Clinically
Significant Difference? Cureus 2020; 12(9): e10523.
https://doi.org/10.7759/cureus.10523
Rashid M, Wu J, Timmis A, Curzen N, Clarke S, Zaman A, et al.
Outcomes of COVID-19-positive acute coronary syndrome
patients: A multisource electronic healthcare records study from
England. J Intern Med 2021; 290(1): 88-100.
https://doi.org/10.1111/joim.13246
Udugama B, Kadhiresan P, Kozlowski HN, Malekjahani A,
Osborne M, Li VYC, et al. Diagnosing COVID-19: The Disease
and Tools for Detection. ACS Nano 2020; 14(4): 3822-3835.
https://doi.org/10.1021/acsnano.0c02624
Guedeney P, Collet JP. Diagnosis and Management of Acute
Coronary Syndrome: What is New and Why? Insight From the
European Society of Cardiology Guidelines. J Clin Med 2020;
(11): 3474. https://doi.org/10.3390/jcm9113474
Puerto E, Viana-Tejedor A, Martínez-Sellés M, Domínguez-Pérez
L, Moreno G, Martín-Asenjo R, et al. Temporal Trends in
Mechanical Complications of Acute Myocardial Infarction in the
Elderly. J Am Coll Cardiol. 2018 Aug 28; 72(9): 959-966.
https://doi.org/10.1016/j.jacc.2018.06.031
Kite TA, Ludman PF, Gale CP, Wu J, Caixeta A, Mansourati J, et
al. International COVID-ACS Registry Investigators. International
Prospective Registry of Acute Coronary Syndromes in Patients
With COVID-19. J Am Coll Cardiol 2021; 77(20): 2466-2476.
https://doi.org/10.1016/j.jacc.2021.03.309
Esposito L, Cancro FP, Silverio A, Di Maio M, Iannece P, Damato
A, et al. COVID-19 and Acute Coronary Syndromes: From
Pathophysiology to Clinical Perspectives. Oxid Med Cell Longev
; 2021: 4936571. https://doi.org/10.1155/2021/4936571
Rowland B, Kunadian V. Challenges in the management of older
patients with acute coronary syndromes in the COVID-19
pandemic. Heart 2020; 106(17): 1296-1301.
https://doi.org/10.1136/heartjnl-2020-317011
Nijjer SS, Petraco R, Sen S. Optimal management of acute
coronary syndromes in the era of COVID-19. Heart 2020; 106(20):