One-Month Mortality in Patients with Ischemic Stroke Using Score for Early Ischemic Stroke Mortality

Authors

  • Maeda Jabeen Department of Medicine, Combined Military Hospital Jhelum/National University of Medical Sciences (NUMS) Pakistan
  • Jamal Waris Department of Medicine, Combined Military Hospital Jhelum/National University of Medical Sciences (NUMS) Pakistan
  • Sehrish Kanwal Department of Medicine, Combined Military Hospital Jhelum/National University of Medical Sciences (NUMS) Pakistan
  • Tasmia Ishaq Department of Medicine, Combined Military Hospital Jhelum/National University of Medical Sciences (NUMS) Pakistan
  • Asad Sufian Azeem Department of Medicine, Combined Military Hospital Jhelum/National University of Medical Sciences (NUMS) Pakistan
  • Farhan Tariq Department of Medicine, Combined Military Hospital Jhelum/National University of Medical Sciences (NUMS) Pakistan

DOI:

https://doi.org/10.51253/pafmj.v74i4.7719

Keywords:

Ischemic stroke, Mortality, Predicting Early Mortality of Ischemic Stroke (PREMISE).

Abstract

Objective: To determine one-month mortality in patients with ischemic stroke using Score for Early Ischemic Stroke Mortality.

Study Design: Prospective longitudinal study.

Place and Duration of Study: Combined Military Hospital, Jhelum Pakistan, from Jan 2020 to May 2021.

Methodology: All patients with acute ischemic stroke, aged more than 18 years, of either gender, were consecutively enrolled. Mortality at 1 month in patients with ischemic stroke was noted along with the demographic and clinical characteristics (comorbidities, smoking status, clinical stroke at admission, and cause of the stroke). Mortality at 1 month was predicted by using Predicting Early Mortality of Ischemic Stroke score. Additionally, National Institutes of Health Stroke Scale, Glasgow Coma Scale, and previous Modified Ranking Scale at admission was also recorded.

Results: Among 160 patients, the Mean age was 66.07±9.92 years. 121(75.6%) patients were males and 39(24.4%) were females. Mortality at 1 month was observed in 26(16.3%) patients. A significant association of mortality at 1 month was observed with age (p<0.001), dyslipidemia (p<0.001), hypertension (p=0.006), carotid stenosis (p<0.001), and atrial fibrillation (p<0.001). A significantly higher mean Predicting Early Mortality of Ischemic Stroke score (p<0.001), National Institutes of Health Stroke Scale score (p<0.001), previous Modified Ranking Scale (p<0.001) was noted among patients in whom mortality was observed at 1 month whereas Glasgow Coma Scale level (p<0.0010.....

Conclusion: The Predicting Early Mortality of Ischemic Stroke scoring system accurately predicted 

Downloads

Download data is not yet available.

References

GBD 2016 Lifetime Risk of Stroke Collaborators. Global, regional, and country-specific lifetime risks of stroke, 1990 and 2016. N Engl J Med 2018; 379(25): 2429-2437.

https://doi.org/10.1056/NEJMoa1804492

Lindsay MP, Norrving B, Sacco RL, Brainin M, Hacke W, Martins S, et al. World Stroke Organization (WSO): global stroke fact sheet 2019. Int J Stroke 2019; 14(8): 806-817.

https://doi.org/10.1177/1747493019881353

Vangen-Lønne AM, Wilsgaard T, Johnsen SH, Løchen ML, Njølstad I, Mathiesen EB et al. Declining incidence of ischemic stroke: what is the impact of changing risk factors? The Tromsø Study 1995 to 2012. Stroke 2017; 48(3): 544-550.

https://doi.org/10.1161/STROKEAHA.116.015313

Wafa HA, Wolfe CD, Emmett E, Roth GA, Johnson CO, Wang Y. Burden of stroke in Europe: thirty-year projections of incidence, prevalence, deaths, and disability-adjusted life years. Stroke 2020; 51(8): 2418-2427.

https://doi.org/10.1161/STROKEAHA.120.029606

Donkor ES. Stroke in the 21st Century: A snapshot of the burden, epidemiology, and quality of life. Stroke Res Treat 2018: 3238165. https://doi.org/10.1155/2018/3238165

Venketasubramanian N, Yoon BW, Pandian J, Navarro JC. Stroke epidemiology in South, East, and South-East Asia: a review. J Stroke 2017; 19(3): 286-94.

https://doi.org/10.5853/jos.2017.00234

Nomani AZ, Nabi S, Badshah M, Ahmed S. Review of acute ischaemic stroke in Pakistan: progress in management and future perspectives. Stroke Vasc Neurol 2017; 2(1): 30-39.

https://doi.org/10.1136/svn-2016-000064

Farooque U, Lohano AK, Kumar A, Karimi S, Yasmin F, Bollampally VC, et al. Validity of National Institutes of Health Stroke Scale for severity of stroke to predict mortality among patients presenting with symptoms of stroke. Cureus 2020; 12(9): e10454.

https://doi.org/10.7759/cureus.10454

Rathore JA, Kango ZA, Mehraj A. Predictors of mortality after acute stroke: a prospective hospital-based study. J Ayub Med Coll Abbottabad 2011; 23(2): 144-146.

Zandieh A, Kahaki ZZ, Sadeghian H, Fakhri M, Pourashraf M, Parviz S, et al. A simple risk score for early ischemic stroke mortality derived from National Institutes of Health Stroke Scale: a discriminant analysis. Clin Neurol Neurosurg 2013; 115(7): 1036-1039.

https://doi.org/10.1016/j.clineuro.2012.11.029

Ahmad A, Usman F, Hassan A. Risk factors and pattern of stroke in Islamabad, Pakistan. Rawal Med J 2009; 34(1): 47-50.

Cadilhac DA, Dewey HM, Vos T, Carter R, Thrift AG. The health loss from ischemic stroke and intracerebral hemorrhage: evidence from the North East Melbourne Stroke Incidence Study (NEMESIS). Health Qual Life Outcomes 2010; 8(1): 49.

https://doi.org/10.1186/1477-7525-8-49

Gattringer T, Posekany A, Niederkorn K, Knoflach M, Poltrum B, Mutzenbach S, et al. Predicting early mortality of acute ischemic stroke: score-based approach. Stroke 2019; 50(2): 349-56. https://doi.org/10.1161/STROKEAHA.118.022004

Ntaios G, Georgiopoulos G, Koroboki E, Vemmos K. External validation of the PREMISE score in the Athens Stroke Registry. J Stroke Cerebrovasc Dis 2019; 28(7): 1806-1809.

https://doi.org/10.1016/j.jstrokecerebrovasdis.2019.03.011

Lecoffre C, de Peretti C, Gabet A, Grimaud O, Woimant F, Giroud M, et al. National trends in patients hospitalized for stroke and stroke mortality in France, 2008 to 2014. Stroke 2017; 48(11): 2939-2945.

https://doi.org/10.1161/STROKEAHA.117.018227

Vaartjes I, O’Flaherty M, Capewell S, Kappelle J, Bots M. Remarkable decline in ischemic stroke mortality is not matched by changes in incidence. Stroke 2013; 44(3): 591-597.

https://doi.org/10.1161/STROKEAHA.112.680843

Tziomalos K, Athyros VG, Karagiannis A, Mikhailidis DP. Dyslipidemia as a risk factor for ischemic stroke. Curr Top Med Chem 2009; 9(14): 1291-1297.

https://doi.org/10.2174/156802609789895722

Luepker RV, Arnett DK, Jacobs Jr DR, Duval SJ, Folsom AR, Armstrong C, et al. Trends in blood pressure, hypertension control, and stroke mortality: the Minnesota Heart Survey. Am J Med 2006; 119(1): 42-49.

https://doi.org/10.1016/j.amjmed.2005.08.008

Wajngarten M, Silva GS. Hypertension and stroke: update on treatment. Eur Cardiol Rev 2019; 14(2): 111-115.

https://doi.org/10.15420/ecr.2019.13.1

Gallacher KI, McQueenie R, Nicholl B, Jani BD, Lee D, Mair FS. Risk factors and mortality associated with multimorbidity in people with stroke or transient ischaemic attack: a study of 8,751 UK Biobank participants. J Comorb 2018; 8(1): 1-8.

https://doi.org/10.15256/joc.2018.8.116

Chao TF, Lip GY, Liu CJ, Lin YJ, Chang SL, Lo LW, et al. Relationship of aging and incident comorbidities to stroke risk in patients with atrial fibrillation. J Am Coll Cardiol 2018; 71(2): 122-132. https://doi.org/10.1016/j.jacc.2017.10.085

Khan MI, Khan JI, Ahmed SI, Ali S. The epidemiology of stroke in a developing country (Pakistan). Pak J Neurol Sci 2019; 13(3): 30-44.

Downloads

Published

30-08-2024

Issue

Section

Original Articles

How to Cite

1.
Maeda Jabeen, Jamal Waris, Sehrish Kanwal, Tasmia Ishaq, Asad Sufian Azeem, Farhan Tariq. One-Month Mortality in Patients with Ischemic Stroke Using Score for Early Ischemic Stroke Mortality. Pak Armed Forces Med J [Internet]. 2024 Aug. 30 [cited 2024 Nov. 22];74(4):1143-6. Available from: https://pafmj.org/PAFMJ/article/view/7719