Mandibular Reconstruction with Vascularized Fibular Graft: Comparing Outcomes of Adjuvant Radiotherapy Versus No-Radiotherapy
Keywords:Fibular graft, Mandibular reconstruction, Non-union, Plate exposure, Radiotherapy
Objective: To compare the outcomes of mandibular reconstruction with vascularized fibular graft in adjuvant and nonradiotherapy Groups.
Study Design: Retrospective longitudinal study.
Place and Duration of Study: Plastic Surgery Department, Shifa International Hospital, Islamabad Pakistan, from 2010 to 2018.
Methodology: The data of 92 patients from 2010-2018 was included. Outcomes regarding local wound complications, wound dehiscence, fistula, skin necrosis, plate exposure and bone union rate were compared in Radiated (IR) and Non-Radiated (NR) Groups. Orthopantomography (OPG) was done at one month, six months, and one-year follow-up and was reviewed by a Radiologist.
Results: Ninety-two patients were included in the study, 56(60.9%) patients in the IR-Group and 36(39.1%) patients in the NRGroup. In the IR-Group, 56(60.9%) causes were intraoral squamous cell carcinoma in 51(91.0%) cases and osteosarcoma in 5(9.0%) cases. In NR-Group cases were ameloblastoma (15,41.6%), giant cell tumor (4,11.1%), craniofacial microsomia
(4,11.1%), osteonecrosis (6,16.6%) and trauma (7,19. 4%). Common complications were plate exposure (2.1%), wound
breakdown (10.8%) in the IR-Group, and, on the other hand, in the NR Group, wound breakdown noted in (3.2%)
Conclusion: With our experience, adjuvant radiation is an important modality that increases survival rate and can be safely
administered without any significant complications related to soft tissue and reconstructed bone.