Concordance between Axillary Ultrasound and Sentinel Biopsy in Clinically Node-Negative Early Breast Cancer

Authors

  • Afroz Mushtaq Department of Surgery, Combined Military Hospital/National University of Medical Sciences (NUMS) Rawalpindi Pakistan
  • Ali Ayesha Khan Department of Surgery, Combined Military Hospital/National University of Medical Sciences (NUMS) Rawalpindi Pakistan
  • Razia Bano Department of Surgery, Combined Military Hospital/National University of Medical Sciences (NUMS) Rawalpindi Pakistan
  • Syeda Rifaat Qamar Naqvi Department of Surgery, Combined Military Hospital/National University of Medical Sciences (NUMS) Rawalpindi Pakistan
  • Shabnum Nawaz Department of Surgery, Combined Military Hospital/National University of Medical Sciences (NUMS) Rawalpindi Pakistan
  • Fahad Ali Khan Department of Surgery, Combined Military Hospital/National University of Medical Sciences (NUMS) Rawalpindi Pakistan
  • Sana Mushtaq Department of Surgery, Pakistan Institute of Medical Sciences, Islamabad Pakistan
  • Palwasha Khan Department of Surgery, Pakistan Institute of Medical Sciences, Islamabad Pakistan

DOI:

https://doi.org/10.51253/pafmj.v73i5.7268

Keywords:

Axillary lymph node dissection, Axillary ultrasound, Clinically impalpable nodes, Early breast cancer, Sentinel lymph node biopsy

Abstract

Objective: To determine the sensitivity of axillary ultrasound in detecting axillary nodal metastasis in clinically and
radiologically uninvolved axillary nodes in early carcinoma breast by comparing with sentinel node biopsy histopathology on frozen section.

Study Design: Comparative cross-sectional study

Place and Duration of Study: Breast Clinic, CMH, Rawalpindi Pakistan, from Aug 2020 to May 2021.

Methodology: Patients included in the study presented with breast cancer lesions with clinically impalpable axillary lymph
nodes aged 18-75. Patients with clinically impalpable nodes underwent an ultrasound of the axilla; if suspicious nodes were
found, the patient had subsequent axillary node dissection. Sentinel node biopsy (SLNB) was performed on axillary
ultrasound in all patients with no suspicious or benign-looking nodes. Histopathological reporting was taken as standard.
Lymph nodal status on axillary ultrasound, SLN biopsy and axillary lymph node clearance were documented and analyzed.

Results: Twenty-nine patients were included who had benign-looking lymph nodes on axillary ultrasound and underwent
sentinel lymph node biopsy. The mean age of the patients was 54.03 ± 7.94. Out of 29 patients, 24(82.8%) patients had negative Sentinel lymph node biopsy, and 5(17.2%) had positive Sentinel lymph node biopsy, who then underwent axillary lymph
node dissection.

Conclusion: Sentinel lymph node biopsy is the gold standard to determine axillary lymph nodes involved in early carcinoma
breast, which seem benign on pre-operative axillary ultrasound.

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Published

30-10-2023

How to Cite

1.
Mushtaq A, Khan AA, Bano R, Naqvi SRQ, Nawaz S, Khan FA, et al. Concordance between Axillary Ultrasound and Sentinel Biopsy in Clinically Node-Negative Early Breast Cancer. Pak Armed Forces Med J [Internet]. 2023 Oct. 30 [cited 2024 May 25];73(5):1330-3. Available from: https://pafmj.org/PAFMJ/article/view/7268

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Original Articles

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