Intravenous Ondansetron Efficacy in Preventing Post Spinal Shivering during Lower Segment Caesarean Section


  • Komail Abid Department of Anesthesia, Combined Military Hospital, Quetta/National University of Medical Sciences (NUMS) Pakistan
  • Rashid Iqbal Department of Anesthesia, Combined Military Hospital/National University of Medical Sciences (NUMS) Rawalpindi Pakistan
  • Syed Ali Raza Shah Department of Cardiac Anesthesia, Armed Forces Institute of Cardiology/National Institute of Heart Diseases/National University of Medical Sciences (NUMS) Rawalpindi Pakistan
  • Sana Tariq Department of Anesthesia, Combined Military Hospital/National University of Medical Sciences (NUMS) Rawalpindi Pakistan



Intravenous ondansetron, Spinal anaesthesia, Post-operative shivering


Objective: To determine IV Ondansetron efficacy in preventing post-spinal shivering during LSCS.

Study Design: Quasi-experimental study.

Place and Duration of Study: Department of Anaesthesiology, Combined Military Hospital, Rawalpindi Pakistan, from Sep
2018 to Mar 2019.

Methodology: A total of 60 women undergoing LSCS under spinal anaesthesia were included. Group-A was given 8 mg/4 ml Ondansetron, while Group-B was given 4 ml Normal Saline 0.9% IV immediately before induction of spinal anaesthesia. Body temperature, level of sensory block, and shivering scores during the peri-operative period were recorded. After surgery, patients were shifted to Post Anaesthesia Care Unit (PACU). Shivering was graded using Crossley and Mahajan 5-item scale. Injection Tramadol 1mg/kg intravenously was used as a rescue anti-shivering drug.

Results: The majority of the patients 33(55.0%) were between 18-25 years of age. Efficacy of Intravenous Ondansetron in
preventing post-operative shivering during spinal anaesthesia in patients undergoing caesarean section was seen in 26
86(67%) patients (Group-A) as compared to 17(56.67%) patients in the Control Group (Group-B) (p-value=0.010).

Conclusion: The study concluded that there was less post-operative shivering with intravenous Ondansetron during spinal
anaesthesia in patients undergoing caesarean section as compared to the Control Group.


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How to Cite

Abid, K., Iqbal, R., Shah, S. A. R., & Tariq, S. (2023). Intravenous Ondansetron Efficacy in Preventing Post Spinal Shivering during Lower Segment Caesarean Section. Pakistan Armed Forces Medical Journal, 73(6), 1636–1639.



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