Association Between Serum Uric Acid Levels and Severe Pre-Eclampsia

Mirza Sijeel Ahmad; Anam  Akram; Mehwish  Gillani; Tariq Ahmed  Maka; Anas Bin  Saif

doi:10.51253/pafmj.v75iSUPPL-1.6674

Authors

Mirza Sijeel Ahmad Department of Anesthesia, Combined Military Hospital, Multan/National University of Medical Sciences (NUMS) Pakistan
Anam Akram Department of Obs & Gyne, Combined Military Hospital, Multan/National University of Medical Sciences (NUMS) Pakistan
Mehwish Gillani Department of Pathology, Pakistan Air Force Hospital, Hyderabad Pakistan
Tariq Ahmed Maka Department of ENT, Combined Military Hospital, Mangla/National University of Medical Sciences (NUMS) Pakistan
Anas Bin Saif Department of Surgery, Combined Military Hospital/National University of Medical Sciences (NUMS) Rawalpindi Pakistan

DOI:

https://doi.org/10.51253/pafmj.v75iSUPPL-1.6674

Keywords:

Hyperuricemia, Pregnancy, Severe pre-eclampsia

Abstract

Objective: To determine the association of hyperuricemia with severe preeclampsia in pregnancy.

Study Design: Prospective Longitudinal study

Place and Duration of Study: Department of Gynecology, Combined Military Hospital, Multan, Pakistan from Mar 2019 to Jul 2019.

Methodology: A total of 68 women with gestational age 20 weeks, parity 0-5, patients with uricemia level ≥5.5mg/dl has been added in exposed group and patients with uricemia level <5.5mg/dl has been added in non-exposed group. Patients were evaluated by detailed history, clinical examination and BP. All relevant findings were documented on a designed proforma. Severe Preeclampsia was noted from both groups.

Results: Women of 18 to 40 years age were selected with mean age of 29.911± 3.49 years in Group A while 31.558± 3.99 years in Group B. Mean gestational age was 23.264±1.84 weeks in Group A and 24.352±1.99 weeks in Group B. Mean serum uricemia level was 6.961±0.74 mg/dl in Group A and 4.635±0.44 mg/dl in Group B. In group A, severe preeclampsia has been seen in 17(50%) womens as compare to 6(17.6%) womens in group B, (p=0.004, R.R=2.8).

Conclusion: This study concluded that the severe pre-eclampsia was associated with hyperuricemic pregnancy.

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