The Prolonged Corrected QT-Interval in Children Presented  with Acute Rheumatic Fever

Malik Abid Ali; Ramchand .; Fazal ur  Rehman; Abdul Sattar  Sheikh; Veena  Kumara; Najma  Patel

doi:10.51253/pafmj.v75iSUPPL-1.6588

Authors

Malik Abid Ali Department of Paeds Cardiology, Rawalpindi Institute of Cardiology, Rawalpindi Pakistan
Ramchand . Department of Paeds Cardiology, National Institute of Cardiovascular Diseases, Karachi Pakistan
Fazal ur Rehman Department of Paeds Cardiology, Pervaiz Elahi Institute of Cardiology Bahawalpur Pakistan
Abdul Sattar Sheikh Department of Paeds Cardiology, National Institute of Cardiovascular Diseases, Karachi Pakistan
Veena Kumara Department of Paeds Cardiology, National Institute of Cardiovascular Diseases, Karachi Pakistan
Najma Patel Department of Paeds Cardiology, National Institute of Cardiovascular Diseases, Karachi Pakistan

DOI:

https://doi.org/10.51253/pafmj.v75iSUPPL-1.6588

Keywords:

Acute Rheumatic fever, Corrected QT-interval, Rheumatic heart disease.

Abstract

Objective: To determine the frequency of prolonged corrected QT-interval on ECG in children presented with acute rheumatic fever.

Study Design: Prospective observational study.

Place and Duration of Study: Department of Paeds Cardiology, National Institute of Cardiovascular Diseases Karachi, Pakistan for six month duration between August 2020 and February 2021.

Methodology: Children presented with features of acute rheumatic fever and fulfilling the selection criteria were enrolled in the study. After getting consent, their demographic details, clinical features, lab values and echo findings were recorded in pro forma. Their 12-lead ECG was analysed by two paediatric cardiology fellows for rhythm and conduction abnormalities at the time of admission and after getting treatment. Bazette’s formula used for calculation of corrected QT-interval, data analysed in SPSS version 21 and presented in tabulated form.

Results: A total of 50 patients were included in the study. There were 31(62%) males and 19(38%) females, 37(74%) patients presented with recurrence and 13(26%) for the first time. On 12-lead ECG corrected QT-interval was prolonged in 14(28%) patients and it was significantly correlated with heart rate of the patients with acute rheumatic fever (p-value 0.027).

Conclusion: Prolonged corrected QT-interval is significantly related with acute rheumatic fever and should be evaluated in each patient of acute rheumatic fever.

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