Efficacy of Timolol Maleate (0.5%) in Preventing Rise of Intraocular Pressure (IOP) Post Neodymium: Yttrium Aluminum Garnet (Nd: YAG) Capsulotomy

Nazia Iqbal; Waqar Muzaffar; Muhammad Haroon Sarfaraz; Saim Khan; Ubaid Ullah Yasin; Farooq Ul Abidin

doi:10.51253/pafmj.v72i1.6219

Authors

Nazia Iqbal Armed Forces Institute of Ophthalmology/National University of Medical Sciences (NUMS) Rawalpindi Pakistan
Waqar Muzaffar Armed Forces Institute of Ophthalmology/National University of Medical Sciences (NUMS) Rawalpindi Pakistan
Muhammad Haroon Sarfaraz POF Hospital, Wah Medical College, Wah/National University of Medical Sciences, Rawalpindi Pakistan
Saim Khan Prince Sultan Military Medical City, Riyadh Kingdom of Saudi Arabia
Ubaid Ullah Yasin Pak Naval Ship Shifa Hospital, Karachi Pakistan
Farooq Ul Abidin Armed Forces Institute of Ophthalmology/National University of Medical Sciences (NUMS) Rawalpindi Pakistan

DOI:

https://doi.org/10.51253/pafmj.v72i1.6219

Keywords:

Intraocular pressure, Neodymium, Posterior capsule opacification, Secondary cataract, Timolol maleate, Yttriumaluminum-garnet (nd: yag) laser posterior capsulotomy

Abstract

Objective: To determine the efficacy of 0.5% Timolol eye drops in preventing rise of intraocular pressure following Neodymium: Yttrium-Aluminum-Garnet laser posterior capsulotomy.

Study Design: Quasi-experimental study.

Place and Duration of Study: Outpatient Department of Ophthalmology, Combined Military Hospital Multan Pakistan, from May to Nov 2019.

Methodology: Patients presenting with posterior capsule opacification, undergoing elective Neodymium: Yttrium Aluminum Garnet (Nd: Yag) Capsulotomy were enrolled in the study. Patients were alternatively assigned to two groups; group-1 was administered 0.5% Timolol Maleate eye drops, while group-2 was administered placebo natural team eye drops. Intraocular pressure for all the patients was measured at three-time points a). First measurement was baseline intraocular pressure at presentation/before the treatment. Second measurement was 1-hour post laser capsulotomy and third measurement was 3 hours post laser capsulotomy.

Results: At 1-hour follow up, the mean intraocular pressure was significantly raised in the patients belonging to control group as compared to treatment group (21.45 ± 8.33 mm Hg vs 15.33 ± 3.37 mm Hg, p<0.001). At 3-hours follow-up the mean intraocular pressure decreased a bit for control group but still was significantly higher than the treatment group (17.40 ± 3.00 mm Hg vs 15.60 ± 2.30 mm Hg, p<0.001).

Conclusion: Prophylactic use of Timolol successfully reduces the post-procedural acute rise in intraocular pressure due to Neodymium: Yttrium Aluminum Garnet laser posterior capsulotomy.