TO DETERMINE CORRELATION BETWEEN MEAN PERIPHERAL LEUCOCYTE COUNTS AND MEAN LESION VOLUME IN ACUTE ISCHEMIC STROKE

Abstract

Objective: To determine correlation between mean peripheral leucocyte counts and mean lesion volume in acute ischemic stroke.

Study Design: Cross sectional study.

Place and Duration of Study: We have performed all this research work Combined Military Hospital Quetta, from Jan 2018 to Dec 2018.

Methodology: All admitted patients fulfilling the inclusion criteria were incorporated in the study. The diagnosis of acute ischemic stroke was based on symptoms of focal neurologic insufficiency and MRI brain evidence of infarct. Total peripheral leucocyte counts were calculated under the supervision of a pathologist who is the fellow of CPSP and has addition a l10 years of experience in pathology. All the above stated evidence including name, age, gender and address were documented in the study Performa.

Results: Total no of patients in our study was 70. Of total patients 39 (55.71%) were male and 31 (4.29%) were females. Correlation between mean peripheral leucocytes counts and mean lesion volume in acute ischemic stroke was calculated as 15.97 ± 3.53 x 109 for TLC and 12.50 ± 3.24 for lesion volume, final results of R are 0.7936. Positive correlation revealed that both increased. X variable scores proportionately related with increased Y variable scores. Same goes for decreased values. The coefficient of determination R2 results turned out to be 0.6298.

Conclusion: We concluded a positive correlation between mean peripheral leucocytes counts and mean lesion volume in acute ischemic stroke. Additional studies are mandatory to validate our findings to establish positive correlation.