Paediatric Liver Transplant at Army Liver Transplant Unit, Pakistan; A Four-Year Data
DOI:
https://doi.org/10.51253/pafmj.v74i1.5804Keywords:
Liver transplantation, Child, Preschool, End Stage Liver Disease, Liver Cirrhosis, cholestasis of pregnancy, Progressive familial intrahepatic 1, Hepatic Insufficiency, MortalityAbstract
Objective: To re-examine the data about survival, prognosis, and complications of twenty-five paediatric liver transplant
procedures carried out at Army Liver Transplant Unit, Pak Emirates Military Hospital Rawalpindi, Pakistan.
Study Design: Retrospective longitudinal study.
Place and Duration of Study: Army Liver Transplant Unit, Pak Emirates Military Hospital, Rawalpindi, Pakistan, from Jan
2016 to Feb 2020.
Methodology: The procedural and follow-up data regarding twenty-five pediatric liver transplants was reviewed, and
demographic variables, transplant indications and outcomes were documented.
Results: The donation was entirely from living donors. Recipients included 12 boys and 13 girls of mean age 5.8±2.00 years.
The stay at the hospital averaged 18±5.6 days. Indications in the order of frequency of encounter included 9(36%) cases of
Cryptogenic liver cirrhosis, 4(16%) cases of progressive familial intrahepatic cholestasis, 3(12%) cases of Wilson’s disease,
2(8%) cases of Tyrosinemia, congenital hepatic fibrosis and biliary atresia each and one patient (4%) of Criggler-Najjar
syndrome, glycogen storage diseases and autoimmune liver disease each. Major complications included viral infections,
thrombosis of the portal vein and hepatic artery, bile leak and post-transplant diaphragmatic hernia. 20(80%) recipients were recorded to have survived during the follow-up.
Conclusion: Encouraging results are noted, particularly a high survival rate (20 out of 25) and low complications (few and
only well-known in this age group).
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