Role of Percutaneous Bone Marrow Aspirate in the Management of Femoral Delayed Union and Non Union Fractures

Abstract

Objective: The objective of the study is to radiologically ascertain bone union following percutaneous autologous bone
marrow aspirate injection in the management of delayed union and non-union fractures of femur.

Study design: Case series.

Duration and place of Study: Department of Orthopedics, Combined Military Hospital, Rawalpindi Pakistan, from Jan to Jun 2019.

Methodology: Forty-two (42) patients of fracture femur who fulfilled the inclusion criteria were enrolled in the study. Fresh
radiographs of affected side were performed to document cases of delayed union and nonunion. 50ml of bone marrow
aspirate from iliac crest was injected at fracture site. Results were evaluated after 12 weeks with the help of radiographs to see radiological union of bone.

Results: A total of 42 patients were included in the study. 37(88.09%) were males and 5(11.9%) were females between the ages of 18 and 60 years. The mean age of patients was calculated to be 34.80±11.17 years. Radiological union was achieved in 32(76.19%) patients.

Conclusion: Radiological assessment shows percutaneous injection of bone marrow as a safe procedure with bone healing in 12 weeks in patients with non-union or delayed union.