Depression in Chronic Obstructive Pulmonary Disease Patients
DOI:
https://doi.org/10.51253/pafmj.v75iSUPPL-2.4635Keywords:
Chronic obstructive airway disease, depression, Patient Health Questionnaire-9 (PHQ-9).Abstract
Objective: To determine the frequency of depression in male Chronic obstructive pulmonary disease patients and various factors.
Study Design: Cross sectional validation study.
Place and Duration of Study: Pak Emirates Military Hospital, Rawalpindi Pakistan, from Aug 2019 to Mar 2020.
Methodology: Fifty male patients who presented with Chronic obstructive pulmonary disease in OPD of Pak Emirates Military Hospital and those who fulfilled the exclusion and inclusion criteria, were included in the study. Informed consent was taken from all these patients and they were asked to fulfill the questionnaire containing Patient Health Questionnaire-9 and other questions related to their disease. Patient Health Questionnaire-9 was taken as a reference scale for depression.
Results: Total 50 patients were included in the study; mean age was 63.9±8 years. Overall frequency of depression in male Chronic obstructive pulmonary disease patients were 75%. Moreover, 25% patients had minimal or no depression, 43.75% patients had mild depression, 26% patients had moderate depression, 5.25% patients had severe depression. It was more common in smokers and ex-smokers. However, a remarkable relationship of depression was established with frequency of disease exacerbations, frequency of inhalers used per day, restriction of daily activities, family support, education and income status.
Conclusion: The presence of depression is common in Chronic obstructive pulmonary disease patients. High index of suspicion should be kept while managing Chronic obstructive pulmonary disease patients. Screening for depression should be done by .....
Downloads
References
Mueller S, Wilke T, Bechtel B, Punekar YS, Mitzner K, Virchow JC. Non-persistence and non-adherence to long-acting COPD medication therapy: a retrospective cohort study based on a large German claims dataset. Respir Med. 2017; 122: 1-1.
Xiao T, Qiu H, Chen Y, Zhou X, Wu K, Ruan X, et al.Prevalence of anxiety and depression symptoms and their associated factors in mild COPD patients from community settings, Shanghai, China: a cross-sectional study. BMC psychiatry. 2018; 18(1): 89.
Matte DL, Pizzichini MM, Hoepers AT, Diaz AP, Karloh M, Dias M, et al. Prevalence of depression in COPD: a systematic review and meta-analysis of controlled studies. Respir Med. 2016; 117: 154-161.
Eissa SA, Essawy TS, Almahdy MA, Mohammed SA, El-Hamady MM. Assessment of the prevalence of depression in chronic obstructive pulmonary disease patients. Egypt J Bronchol. 2018; 12(2): 187.
Lecheler L, Richter M, Franzen DP, Rampini SK, Cheetham M, Jenewein J, et al. The frequent and underrecognised co-occurrence of acute exacerbated COPD and depression warrants screening: a systematic review. Eur Respir Rev.2017; 26(144): 170026.
Kim KU, Park HK, Jung HY, Ahn JJ, Moon E, Kim YS, et al Association of depression with disease severity in patients with chronic obstructive pulmonary disease. Lung. 2014; 192(2): 243-249.
De S. Prevalence of depression in stable chronic obstructive pulmonary disease. Indian J Chest Dis Allied Sci. 2011; 53(1): 35.
Thapa N, Maharjan M, Shrestha TM, Gauchan S, Pun P, Thapa YB. Anxiety and depression among patients with chronic obstructive pulmonary disease and general population in rural Nepal. BMC psychiatry. 2017; 17(1): 397.
Thapa N, Maharjan M, Shrestha TM, Gauchan S, Pun P, Thapa YB. Anxiety and depression among patients with chronic obstructive pulmonary disease and general population in rural Nepal. BMC psychiatry. 2017; 17(1): 397.
Cafarella PA, Effing TW, USMANI ZA, Frith PA. Treatments for anxiety and depression in patients with chronic obstructive pulmonary disease: a literature review. Respirology. 2012; 17(4): 627-638.
Over 6.9 million people suffer from COPD in Pakistan: expert [Internet]. Business Recorder. [cited 2020May18]. Available from: https://fp.brecorder.com/2015/11/201511171247450/
Van Manen JG, Bindels PJ, Dekker FW, IJzermans CJ, Van der Zee JS, Schade E. Risk of depression in patients with chronic obstructive pulmonary disease and its determinants. Thorax. 2002; 57(5): 412-416.
Laurin C, Moullec G, Bacon SL, Lavoie KL. Impact of anxiety and depression on chronic obstructive pulmonary disease exacerbation risk. Am J Respir Crit Care Med. 2012; 185(9): 918-923.
Tetikkurt C, Ozdemir I, Tetikkurt S, Yılmaz N, Ertan T, Bayar N. Anxiety and depression in COPD patients and correlation with sputum and BAL cytology. Multidiscip Respir Med. 2011; 6(4): 226.
Yu T, Frei A, Ter Riet G, Puhan MA. Impact of stressful life events on patients with chronic obstructive pulmonary disease. Respiration. 2018; 95(2): 73-79.
Gado O, Basiony L, Ibrahim M, Shady I, Affara N. Anxiety-depressive symptoms in patients with chronic obstructive pulmonary disease (COPD) and impact on outcome. J Depress Anxiety. 2015; 4(2): 1-6.
Hill K, Geist R, Goldstein RS, Lacasse Y. Anxiety and depression in end-stage COPD. Eur Respir J 2008; 31(3): 667-677.
Mueller S, Wilke T, Bechtel B, Punekar YS, Mitzner K, Virchow JC. Non-persistence and non-adherence to long-acting COPD medication therapy: a retrospective cohort study based on a large German claims dataset. Respir Med 2017; 122: 1-1.
Kim KU, Park HK, Jung HY, Ahn JJ, Moon E, Kim YS, et al. Association of depression with disease severity in patients with chronic obstructive pulmonary disease. Lung 2014; 192(2): 243-249.
Downloads
Published
Issue
Section
License
Copyright (c) 2025 Saba Daud Malik, Shazia Nisar

This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.