Comparison of Post Extubation Cough with Instillation of 2% Lidocaine Versus air in Endotracheal Tube
Keywords:Endotracheal tube, Extubation, Lidocaine, Post-operative cough
Objective: To determine the efficacy of 2% Lidocaine instillation for endotracheal tube cuff inflation versus air on postextubation cough.
Study Design: Quasi-experimental study.
Place and Duration of Study: Combined Military Hospital, Rawalpindi Pakistan, from May to Nov 2018.
Methodology: The study was carried out on 64 patients undergoing surgery under general anaesthesia of a duration greater than one hour. Patients with respiratory pathology, risk of aspiration, difficult airway, and who need postop ventilator support were excluded. Patients were divided into Group-A (inflated with air) and Group-L (inflated with 2% Lidocaine) by sealed opaque envelop method. Post-extubation cough and one hour later was recorded.
Results: The mean age of Group-A and Group-L was 30.06±4.36 years and 29.66±4.45 years, respectively. 43(67.19%)
participants were males, whereas 21(32.81%) were females. The efficacy of 2% Lignocaine versus air in endotracheal cuff on
post-extubation cough and one hour following extubation in Group-A was 19(59.38%) and 11(34.38%), respectively. This was reduced to 06(18.75%) and 1(3.13%) in Group-L, respectively (p<0.05).
Conclusion: This study concluded that using 2% Lidocaine for inflation of the endotracheal tube cuff decreases the cough
frequency after extubation compared to air.