FREQUENCY OF HYPERURICEMIA IN THYROID DYSFUNCTION

Hyperuricemia

Abstract

Objective: To determine the frequency of hyperuricemia in patients with thyroid dysfunction.
Study Design: Cross-sectional descriptive study.
Place and Duration of Study: Department of Chemical Pathology, Army Medical College Rawalpindi, National University of Sciences & Technology (NUST) Islamabad and Military Hospital (MH) Rawalpindi, from Apr 2013 to Jun 2014.
Results: Among the fifty five participants, 16 (29.1%) were male while 39 (70.9%) were females. Mean age of the subjects was 45.49 ± 16.7 years in this study. Hyperuricemia was observed in seventeen (30.9%) individuals with thyroid dysfunction. Mean serum uric acid level was found to be 418.3 ± 147 µmol/l in participants.
Material and Methods: Fifty five individuals with thyroid dysfunction were included in this study. Detailed history was recorded on a questionnaire, blood samples were collected and serum total tri-iodothyronine (T3), free thyroxine (T4), thyroid stimulating hormone (TSH) and uric acid levels were measured.
Conclusion: High frequency of hyperuricemia occurs in patients with thyroid dysfunction. Therefore in patients presenting with thyroid dysfunction, evaluation of underlying hyperuricemia should be considered by the clinicians.