Type & Frequency of Lymphomas: Single Institution Experience

Abstract

Objective: To see the type and frequency of lymphomas.

Study Design: Prospective longitudinal study.

Place and Duration of Study: Department of Medical Oncology at Jinnah Postgraduate Medical Centre, Karachi from Jan 2019 to Dec 2019.

Methodology: Total of 150 patients with histopathological diagnoses of lymphoma of 17 to 71 years of age of either gender were included in the study using non-probability consecutive sampling technique. Prior to initiation of study ethics review committee has approved the study (NO.F.2-81-IRB/2019-GENL/10261/JPMC). The data regarding lymphoma type, histology, stage of disease, site, involvement of bone marrow, presence of B-symptoms were recorded.

Results: Majority of the patients were male i.e., (n=104, 69.3%) with the mean age of 45.29±17.76 years. Non-Hodgkin’s
Lymphoma presented as the most common type of lymphoma i.e., (n=107, 71.3%) whereas Hodgkin’s lymphoma (HL)
contributed for (n=43, 28.7%) cases. Assessment of clinicopathological features of lymphomas revealed that (n=58, 38.7%)
cases had bone marrow involvement. B-symptoms appeared in (n=102, 68%) cases, (n=61, 40.7%) cases were stage IV and the most common site were Neck lymph nodes (n=82, 58.3%), followed by abdomen (n=20, 13.3%). There was statistically
significant difference between type of lymphoma with respect to age (p=0.001) and gender(p=0.015)

Conclusion: Among lymphomas the most common type of lymphoma was Non-Hodgkin’s Lymphoma, most common in
patients >45 years of age showing relationship of its occurence with age and..