The Spectrum of Malignant Tumours at a Tertiary Care Hospital in Rawalpindi
DOI:
https://doi.org/10.51253/pafmj.v74i6.2786Keywords:
Breast Neoplasms, Neoplasms, Prostatic Neoplasms, Tumor Registry Data.Abstract
Objective: To determine the frequency of malignant tumors seen in our practice and to provide a foundation for building a comprehensive cancer care strategy.
Study Design: Cross-sectional study.
Place and Duration of Study: Histopathology Department, Armed Forces Institute of Pathology Rawalpindi, Pakistan from 2009 to 2018.
Methodology: All malignant tumors reported from 2009-2018 were retrieved from our tumor registry. This data was analyzed for overall frequency gender distribution, age groups and type/site relationship. Present data was also compared with recent and previous such analyses done both nationally and worldwide, in similar settings and demographics.
Results: Total 37793 malignant tumors were diagnosed and registered. Out of this, 22077(58.4%) were males and 15716(41.5%) were females. The most common cancer reported was breast (14.3%) followed by urinary bladder (8.7%), oral (6.7%), lymph nodular (5.5%) and prostatic (5.3%). Malignant tumors in pediatric age group (0-14 years) were found to be 3.4%. Most malignancies were reported in 6th decade of life.
Conclusion: There was increase in the total number of the malignant tumors during 2009-2018, as compared to the previous 10 years’ data. Male to female ratio was 1.4:1. The five most common sites in male were urinary bladder, prostate, skin, lymph nodes and oral cavity and pharynx. Whereas in females these were breast, skin, oral cavity, female genital organs (ovary) and lymph nodes.
Downloads
References
World Health Organization. Cancer [Internet]. Available from:
https://www.who.int/news-room/fact-sheets/detail/cancer
Stimpfel M, Virant-Klun I. Cancer incidence and mortality worldwide: Sources, methods and major patterns in Globocan 2012. J. Cancer Stem Cell Res 2016; 4(3): 1.
https://doi.org/10.14343/jcscr.2016.4e1003
Allemani C, Matsuda T, Di Carlo V, Harewood R, Matz M, Nikšić M, et al. Global surveillance of trends in Cancer survival 2000–14 (Concord-3): Analysis of individual records for 37 513 025 patients diagnosed with one of 18 cancers from 322 population-based registries in 71 countries. Lancet 2018; 391(10125): 1023–1075.
https://doi.org/10.1016/S0140-6736(17)33326-3
UICC 2022. Global cancer data: Globocan 2018 [Internet]. Available from:
https://www.uicc.org/news/global-cancer-data-globocan-2018
McGuire S. World cancer report 2014. Geneva, Switzerland: World Health Organization, International Agency for Research on Cancer, who press, 2015. Adv. Nutr 2016; 7(2): 418–419.
https://doi.org/10.3945/an.116.012211
Ahmad M, Khan AH, Mansoor A. The pattern of malignant tumours in northern Pakistan. J Pak Med Assoc 1991; 41(11): 270-273.
Jamal S, Moghal S, Mamoon N, Mushtaq S, Luqman M, Anwar M, et al. The pattern of malignant tumours: tumour registry data analysis, AFIP, Rawalpindi, Pakistan (1992-2001). J Pak Med Assoc 2006; 56(8): 359.
Khadim MT, Jamal S. Cancer Data Statistics: AFIP Monograph (Fourth Edition) Review. Pak J Pathol 2019; 29(4): 60.
Pervez S, Jabbar AA, Haider G, Ashraf S, Qureshi MA, Lateef F, et al. Karachi cancer registry (KCR): Age-Standardized incidence rate by age-group and gender in a Mega city of Pakistan. Asian Pac J Cancer Prev 2020; 21(11): 3251.
https://doi.org/10.31557/APJCP.2020.21.11.3251
Shahid M, Raqib F, Aneel Y, Ain ul Q, Hina A, Adna A, et al. Collective cancer registry report from December till December of the 1994 – 2017 [Internet]. Available from:
https://shaukatkhanum.org.pk/wp
UICC. 2022]. Globocan 2020: New Global Cancer Data [Internet]. Available from:
https://www.uicc.org/news/globocan-2020-new-global-cancer-data
Pervez, Shahid. Most cancers are caused by bad luck mutations: scientific explanation? J. Cancer Allied Spec 2019; 5.
https://doi.org/10.37029/jcas.v5i1.229
Badar F, Mahmood S. Cancer in Lahore,Pakistan, 2010–2019: an incidence study. BMJ Open 2022; 11: e047049.
https://doi.org/10.1136/bmjopen-2020-047049
Jahan N. Fast food consumption drift in Pakistani population. J Food Nutr Sci 2014; 2(1): 13-18.
https://doi.org/10.11648/j.jfns.20140201.12
Pervez, S., Abro, B. Oral Cancer and Chewing Habits. In: Al Moustafa, AE. (eds) Development of Oral Cancer. Springer 2017. https://doi.org/10.1007/978-3-319-48054-1_8
Mummudi N, Agarwal JP, Chatterjee S, Mallick I, Ghosh-Laskar S. Oral cavity cancer in the Indian subcontinent – challenges and opportunities. Clin Oncol 2019; 31(8): 520–528.
https://doi.org/10.1016/j.clon.2019.05.013
Qureshi MA. Revival of cancer registration in Karachi, Pakistan. Asian Pac J Cancer Prev 2021; 22(1): 1–1.
https://doi.org/10.31557/APJCP.2021.22.1.1
Sajjad M, Bhatti A, Hill B, Al-Omari B. Using the theory of planned behavior to predict factors influencing fast-food consumption among college students. BMC Public Health 2023; 23(1): 987. https://doi.org/10.1186/s12889-023-15923-1
Downloads
Published
Issue
Section
License
Copyright (c) 2024 Muhammad Tahir Khadim, Bushra Parveen, Hafeez Ud Din, Amna Ameer, Ayesha Arif
This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.