ASSOCIATION OF VITAMIN D DEFICIENCY WITH POLYCYSTIC OVARIAN SYNDROME

Abstract

Objective: To determine the frequency of vitamin D deficiency in women with polycystic ovary syndrome.

Study Design: Cross sectional study.

Place and Duration of Study: Department of Obstetrics and Gynecology, Combined Military Hospital Lahore, from Apr 2018 to Sep 2018.

Material and Methods: This study involved 200 women aged between 18-45 years presenting with polycysticovarian syndrome. Blood sample was analyzed for vitamin D level and serum levels of 25-hydroxy VitaminD3<20ng/ml were labeled as vitamin D deficiency. A written informed consent was obtained from every patient. All the collected data was entered and analyzed through SPSS version 20.

Results: The age of the patients ranged from 18 years to 45 years with a mean of 26.82 ± 7.67 years. Majority(n=148, 74.0%) of the patients were aged between 18-31 years followed by 32-45 years (n=52, 26.0%). There were 92 (46.0%) obese patients in the study group. The frequency of vitamin D deficiency was found to be 58.0% in women suffering from PCOS. There was no significant difference in the frequency of vitamin D deficiency among age groups; 18-31 vs. 32-45 years (58.1% vs. 57.7%; p=0.958) and BMI groups; obese vs. non-obese (65.2% vs. 51.9%; p=0.056).

Conclusion: The frequency of vitamin D deficiency was found to be 58.0% in women suffering from PCOS. There was no significant difference in the frequency of vitamin D deficiency among age and BMI groups.