Socio-Demographic Predictors of Psoriasis; a Comparative Study Between Patients with Paediatric-Onset Psoriasis and Adult-Onset Psoriasis in Pakistan
DOI:
https://doi.org/10.51253/pafmj.v75i1.12550Keywords:
Age of onset, Comorbidities, Children, Depression, Gender, Genetic predisposition, Mental health, Psoriasis, Prevalence.Abstract
Objective: To compare pediatric-onset psoriasis and adult-onset psoriasis in terms of frequency of gender involved, family history, trigger factors, and sites involved at onset.
Study Design: Comparative cross-sectional study.
Place and Duration of Study: Department of Dermatology, Pak Emirates Military Hospital, Rawalpindi Pakistan from Apr to Oct 2021.
Methodology: A total of 175 patients with psoriasis, aged 1 to 60 years, of either gender were included. Patients were divided into pediatric and adult Groups. In all patients, gender involved, family history, trigger factors, and sites involved at onset were noted.
Results: Our study reported that the majority of the respondents in the Adult Onset Psoriasis Patients Group and the Pediatric Onset Psoriasis patients (Adult Onset Psoriasis Patients) Group were males, and their percentages were 63.85% and 60.0%, respectively. In the POPPs Group, the scalp (48.89%), elbows (35.56%), and knees (11.11%) were most commonly involved at onset, similar to the AOPPs Group, where also the scalp (48.46%), elbows (22.31%) and the knees (18.46%) were the top three sites involved at the onset. In the POPP Group, 55.56% of patients had a history of psoriasis in their family compared to 58.46% of the AOPP Group. In the POPP Group, 28.89% had some trigger factor compared to 26.92% of the AOPP Group.
Conclusion: This study identifies key differences between pediatric-onset and adult-onset psoriasis, with scalp and elbows as common sites and knees more frequently involved in adults. Pediatric cases showed a slightly higher prevalence of trigger factors,
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References
Armstrong AW, Read C. Pathophysiology, Clinical Presentation, and Treatment of Psoriasis: A Review. JAMA 2020; 323(19): 1945-1960. https://doi.org/10.1001/jama.2020.4006
Raharja A, Mahil SK, Barker JN. Psoriasis: a brief overview. Clin Med 2021; 21(3): 170-173.
https://doi.org/10.7861/clinmed.2021-0257
Reid C, Griffiths CEM. Psoriasis and Treatment: Past, Present and Future Aspects. Acta Derm Venereol 2020; 100(3): adv00032.
https://doi.org/10.2340/00015555-3386
Armstrong AW, Mehta MD, Schupp CW, Gondo GC, Bell SJ, Griffiths CEM. Psoriasis Prevalence in Adults in the United States. JAMA Dermatol 2021; 157(8): 940-946.
https://doi.org/10.1001/jamadermatol.2021.2007
Takeshita J, Grewal S, Langan SM, Mehta NN, Ogdie A, Van Voorhees AS, et al. Psoriasis and comorbid diseases: epidemiology. J Am Acad Dermatol 2017; 76: 377–390.
https://doi.org/10.1016/j.jaad.2016.07.064
Mina AM, Erica BL, Tsen-Fang TS, Jashin JW. Psoriasis and co-morbidity. Acta Derm Venereol 2020; 100(3): 5650.
Bu J, Ding R, Zhou L, Chen X, Shen E. Epidemiology of Psoriasis and Comorbid Diseases: A Narrative Review. Front Immunol 2022; 13: 880201. https://doi.org/10.3389/fimmu.2022.880201
Wu JJ, Kavanaugh A, Lebwohl MG, Gniadecki R, Merola JF. Psoriasis and metabolic syndrome: implications for the management and treatment of psoriasis. J Eur Acad Dermatol Venereol 2022; 36(6): 797-806.
https://doi.org/10.1111/jdv.18044
Michalek IM, Loring B, John SM. A systematic review of worldwide epidemiology of psoriasis. J Eur Acad Dermatol Venereol 2017; 31(2): 205-212.
https://doi.org/10.1111/jdv.13854
Mercy K, Kwasny M, Codoro KM, Menter A, Tom WL, Korman N, et al. Clinical Manifestations of pediatric psoriasis: results of a multicenter study in the United States. Pediatr Dermatol 2013; 30(4): 424-428. https://doi.org/10.1111/pde.12072
Chiam LY, de Jager ME, Giam YC, de Jong EM, van de Kerkhof PC, Seyger MM, et al. Juvenile psoriasis in European and Asian children: similarities and differences. Br J Dermatol 2011: 164(5): 1101-1103.
https://doi.org/10.1111/j.1365-2133.2010
Iskandar IY, Parisi R, Griffiths CE, Ashcroft DM, Global Psoriasis Atlas. Systematic review examining changes over time and variation in the incidence and prevalence of psoriasis by age and gender. Br J Dermatol 2021; 184(2): 243-258.
https://doi.org/10.1111/bjd.19169
Huang YW, Tsai TF. HLA-Cw1 and psoriasis. Am J Clin Dermatol 2021; 22(3): 339-347.
https://doi.org/10.1007/s40257-020-00585-1
Tsoi LC, Stuart PE, Tian C. Large scale meta-analysis characterizes genetic architecture for common psoriasis associated variants. Nat Commun 2017; 8: 15382.
https://doi.org/10.1038/ncomms15382
Tollefson MM, Crowson CS, McEvoy MT, Kremers HM. Incidence of psoriasis in children: a population-based study. J Am Acad Dermatol 2010; 62(6): 979-987.
Ogawa K, Okada Y. The current landscape of psoriasis genetics in 2020. J Dermatol Sci 2020; 99 (1): 2-8.
Ozden MG, Tekin NS, Gürer MA, Akdemir D, Doğramacı C, Utaş S, et al. Environmental risk factors in pediatric psoriasis: a multicenter case-control study. Pediatr Dermatol 2011; 28(3): 306-312. https://doi.org/10.1111/j.1525-1470.2011.01408.x
Hrehorów E, Salomon J, Matusiak L, Reich A, Szepietowski JC. Patients with psoriasis feel stigmatized. Acta Derm Venereol 2020; 100(8): adv00147. https://doi.org/10.2340/00015555-1193
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