Spontaneous Mandibular Regeneration Following Segmental Mandibulectomy: A Case Report

Sanya Javaid; Zubair  Durrani; Muhammad Imran

doi:10.51253/pafmj.v75i6.12230

Authors

Sanya Javaid Department of Oral and Maxillofacial Surgery, Rehman College of Dentistry, Peshawar Pakistan
Zubair Durrani Department of Oral and Maxillofacial Surgery, Rehman College of Dentistry, Peshawar Pakistan
Muhammad Imran Department of Oral and Maxillofacial Surgery, Rehman College of Dentistry, Peshawar Pakistan

DOI:

https://doi.org/10.51253/pafmj.v75i6.12230

Keywords:

Arteriovenous Malformation, Bone Tissue Engineering, CT Angiography, Hemimandibulectomy

Abstract

An 8-year-old male presented with profuse oral cavity bleeding, leading to diagnosis of a large arteriovenous malformation involving the hemimandible and extending into the infratemporal fossa. After optimization and arterial embolization, he underwent hemi-mandibular resection, with spontaneous mandibular regeneration observed at 6-month follow-up. This case highlights spontaneous mandibular regeneration (SMR), a rare phenomenon primarily reported in children, influenced by periosteum preservation. Literature underscores age as a key factor, alongside occurrences in medication-related osteonecrosis of the jaw (MRONJ), with implications for bone tissue engineering (BTE) in mandibular reconstruction. SMR offers potential to overcome traditional reconstructive limitations, warranting further research in oral and maxillofacial surgery.

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