Impact of Migraine on Symptoms of Fibromyalgia
DOI:
https://doi.org/10.51253/pafmj.v74iSUPPL-2.11783Keywords:
Aura, Fibromyalgia, Health Impact test, Headache, Migraine, Pain thresholdAbstract
Objective: To determine the frequency of fibromyalgia in patients of migraine and to see the impact of migraine on symptoms
of fibromyalgia.
Study Design: Cross sectional study.
Place and Duration of Study: Department of Medicine, Combined Military Hospital, Peshawar Pakistan, from Sep 2023 to Feb
2024.
Methodology: The number of patients that were included in the study were 109. Every patient underwent detailed history
taking which included information regarding demographic characteristics, clinical characteristics. Diagnosis of fibromyalgia
was done with the help of 2016 American College of Rheumatology classification criteria. Headache Impact test-6 was used to
assess the impact of headache on patient life. Headache intensity was assessed with the help of visual analogue scale (0-10).
FIQR score was used to classify the severity of fibromyalgia.
Results: In this study fibromyalgia was diagnosed in 40(36.7%) patients. Duration of migraine, migraine frequency, headache
intensity and Headache impact severity score showed significant difference in patients without and without fibromyalgia.
Fibromyalgia’s assessment was done with the help of FIQR score. The three domains of this score showed that patients
experience worsening due to fibromyalgia in terms of function (Median =21), overall impact (Median=13) and symptoms
(Median=38.50) and total score (Median=73.50).
Conclusion: Results of this study demonstrate high frequency of fibromyalgia in migraine patients. Patients with migraine and
fibromyalgia showed higher frequency for migraine attacks and Fibromyalgia impact questionnaire score.
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References
Del Rio MS, Cutrer FM. Pathophysiology of migraine aura.
Handbook of Clinical Neurology. 198: Elsevier; 2023. p. 71-83.
https://doi.org/10.1016/B978-0-12-823356-6.00016-0
Hovaguimian A, Roth J. Management of chronic migraine. bmj.
;379. doi:https://doi.org/10.1136/bmj-2021-067670
Gazerani P. Migraine and diet. Nutrients. 2020; 12(6): 1658.
https://doi.org/10.3390/nu12061658
Ashina S, Bentivegna E, Martelletti P, Eikermann-Haerter K.
Structural and functional brain changes in migraine. Pain and
therapy. 2021; 10: 211-23.
https://doi.org/10.1007/s40122-021-00240-5
Kung D, Rodriguez G, Evans R. Chronic migraine: diagnosis and
management. Neurologic Clinics. 2023 Feb 1; 41(1): 141-59. doi:
1016/j.ncl.2022.05.005.
Moon H-S, Park K-Y, Chung J-M, Kim B-K. An Update On Migraine
Treatment. Journal of the Korean Neurological Association. 2020;
(2): 100-10.
https://doi.org/10.17340/jkna.2020.2.3
Gur M, Gulkesen A, Akgol G. Comparison of ACR 1990 and ACR
classification criteria in fibromyalgia syndrome. Med Science.
;8(4):975-9. doi:10.5455/medscience.2019.08.9083
Gyorfi M, Rupp A, Abd-Elsayed A. Fibromyalgia pathophysiology.
Biomedicines. 2022; 10(12): 3070
.https://doi.org/10.3390/biomedicines10123070
Saracoglu I, Akin E, Aydin Dincer GB. Efficacy of adding pain
neuroscience education to a multimodal treatment in fibromyalgia:
A systematic review and meta‐analysis. International Journal of
Rheumatic Diseases. 2022; 25(4): 394-404. doi: 10.1111/1756-
X.14293.
Younis A, Qasem Y, Ali Neamat Sulaiman A. The Frequency of
Fibromyalgia in Migraine Patients. Open Access Macedonian Journal
of Medical Sciences. 2022; 10(B): 260-4.
https://doi.org/10.3889/oamjms.
Arnold M. Headache Classification Committee of the International
Headache Society (IHS) The International Classification of Headache
Disorders, 3rd edition. Cephalalgia. 2018; 38(1): 1-211. doi:
1177/0333102417738202.
Ahmed S, Aggarwal A, Lawrence A. Performance of the American
College of Rheumatology 2016 criteria for fibromyalgia in a referral
care setting. Rheumatology international. 2019; 39(8): 1397-403.
https://doi: 10.1007/s00296-019-04323-7
Houston MN, Bookbinder HA, Roach SP, Ross JD, Aderman MJ,
Peck KY, et al. Reference values for the headache impact test-6
questionnaire. Archives of physical medicine and rehabilitation.
; 102(12): 2369-76.
https://doi.org/10.1016/j.apmr.2021.05.013
Beyazal MS, Tüfekçi A, Kırbaş S, Topaloğlu MS. The impact of
fibromyalgia on disability, anxiety, depression, sleep disturbance,
and quality of life in patients with migraine. Archives of
Neuropsychiatry. 2018 Jun; 55(2): 140.
https://doi: 10.5152/npa.2016.12691
Hsu Y-W, Liang C-S, Lee J-T, Chu H-T, Lee M-S, Tsai C-L, et al.
Associations between migraine occurrence and the effect of aura, age
at onset, family history, and sex: A cross-sectional study. Plos one.
;15(2):e0228284.
https://doi:10.1371/journal.pone.0228284
Allais G, Chiarle G, Sinigaglia S, Airola G, Schiapparelli P, Benedetto
C. Gender-related differences in migraine. Neurological Sciences.
; 41: 429-36.
https://doi.org/10.1007/s10072-020-04643-8
Buse DC, Loder EW, Gorman JA, Stewart WF, Reed ML, Fanning
KM, et al. Sex differences in the prevalence, symptoms, and
associated features of migraine, probable migraine and other severe
headache: results of the American Migraine Prevalence and
Prevention (AMPP) Study. Headache. 2013; 53(8): 1278-99.
https://doi: 10.1111/head.12150
Hatami M, Soveid N, Lesani A, Djafarian K, Shab-Bidar S. Migraine
and obesity: Is there a relationship? A systematic review and metaanalysis of observational studies. CNS & Neurological DisordersDrug Targets (Formerly Current Drug Targets-CNS & Neurological
Disorders). 2021; 20(9): 863-70.
Onder H, Hamamci M, Alpua M, Ulusoy EK. Comorbid
fibromyalgia in migraine patients: clinical significance and impact on
daily life. Neurological Research. 2019; 41(10): 909-15.
Rehm S, Sachau J, Hellriegel J, Forstenpointner J, Jacobsen HB,
Harten P, et al. Pain matters for central sensitization: sensory and
psychological parameters in patients with fibromyalgia syndrome.
Pain Reports. 2021; 6(1): e901.
https://doi: 10.1097/PR9.0000000000000901
Whealy M, Nanda S, Vincent A, Mandrekar J, Cutrer FM.
Fibromyalgia in migraine: a retrospective cohort study. J Headache
Pain. 2018;19(1): 61.
https://doi: 10.1186/s10194-018-0892-9.
Giamberardino MA, Affaitati G, Martelletti P, Tana C, Negro A,
Lapenna D, et al. Impact of migraine on fibromyalgia symptoms. J
Headache Pain. 2015; 17: 28.
https://doi:10.1186/s10194-016-0619-8
Hansen JM, Charles A. Differences in treatment response between
migraine with aura and migraine without aura: lessons from clinical
practice and RCTs. J Headache Pain. 2019 Sep 6; 20(1): 96.
https://doi: 10.1186/s10194-019-1046-4.
Di Carlo M, Farah S, Bazzichi L, Atzeni F, Govoni M, Biasi G, et al.
AB0716 Fibromyalgia Syndrome Severity According To Age
Categories: Results From A National Register. BMJ Publishing
Group Ltd; 2021. https://doi.org/10.1136/annrheumdis-2021-
eular.150
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