Role of Preoperative Intravenous Steroid Injection in Preventing Seroma Formation After Breast Surgeries

Authors

  • Shaza Bashir Department of General Surgery, Armed Forces Post Graduate Medical Institute/National University of Medical Sciences (NUMS), Rawalpindi Pakistan
  • Syed Mukarram Hussain Department of General Surgery, Combined Military Hospital/National University of Medical Sciences (NUMS), Rawalpindi Pakistan
  • Waseem Ahmad Khan Department of General Medicine, Pak Emirates Military Hospital/National University of Medical Sciences (NUMS), Rawalpindi Pakistan
  • Muhammad Ahmad Department of General Surgery, Armed Forces Post Graduate Medical Institute/National University of Medical Sciences (NUMS), Rawalpindi Pakistan
  • Adil Maqbool Department of General Surgery, Armed Forces Post Graduate Medical Institute/National University of Medical Sciences (NUMS), Rawalpindi Pakistan
  • Fawad Anwar Department of General Surgery, Armed Forces Post Graduate Medical Institute/National University of Medical Sciences (NUMS), Rawalpindi Pakistan

DOI:

https://doi.org/10.51253/pafmj.v75i5.11734

Keywords:

Breast Surgery, Depomedrol, Methylprednisolone, Seroma, Steroids

Abstract

Objective: To evaluate the role of preoperative intravenous steroid injection in preventing seroma formation after breast surgeries.

Study Design: Quasi-experimental study.

Place and Duration of Study: Pak Emirates Military Hospital, Rawalpindi Pakistan, from Jul to Dec 2023.

Methodology: With non-probability consecutive sampling technique, a total of 40 patients were included who were scheduled for breast surgeries. 20 patients were grouped into Group-I who were not given steroid before surgery. Group-II also consisted of 20 patients who were injected 120 mg intravenous injection of methylprednisolone one hour prior to surgery. Post-surgery the amount of drainage and number of drainage days were recorded in milliliters. At each follow up visit, wound was also examined for any infection or necrosis.

Results: Patients ranged in age from 18 to 69 years, with a mean age of 56.83+6.91. Methylprednisolone injection given to the patients of Group-II helped reduce the average drain output and number of days for which drainage was required and was statistically significant. 25% of patients reported with seroma formation in Group-II and only 5% of which underwent surgical/ IR guided intervention as compared to 45% in Group-I with 15% undergoing surgical/ IR guided intervention.

Conclusion: A single dose of intravenous steroid injection (methylprednisolone) given an hour before surgery is a promising and effective strategy to prevent seroma formation following breast surgical procedures without any significant complications or side effects.

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Published

31-10-2025

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Original Articles

How to Cite

1.
Bashir S, Hussain SM, Khan WA, Ahmad M, Maqbool A, Anwar F. Role of Preoperative Intravenous Steroid Injection in Preventing Seroma Formation After Breast Surgeries. Pak Armed Forces Med J [Internet]. 2025 Oct. 31 [cited 2025 Nov. 2];75(5):1000-3. Available from: https://pafmj.org/PAFMJ/article/view/11734