Electrocardiogram (ECG) Pattern of Left Anterior Descending Coronary Artery Occlusion in Acute Anterior Myocardial Infarction Cases

Authors

  • Zeeshan Ishaq Department of Cardiology, Armed forces Institute of Cardiology/National Institute of Heart Diseases/National University of Medical Sciences (NUMS) Pakistan
  • Asif Nadeem Department of Cardiology, Armed forces Institute of Cardiology/National Institute of Heart Diseases/National University of Medical Sciences (NUMS) Pakistan
  • Nisar Ahmed Department of Cardiology, Combined Military Hospital Sargodha/National University of Medical Sciences (NUMS) Pakistan
  • Iftikhar Ahmed Department of Cardiology, Armed forces Institute of Cardiology/National Institute of Heart Diseases/National University of Medical Sciences (NUMS) Pakistan
  • Zahid Mumtaz Department of Cardiology, Armed forces Institute of Cardiology/National Institute of Heart Diseases/National University of Medical Sciences (NUMS) Pakistan
  • Naseem Azad Department of Cardiology, Armed forces Institute of Cardiology/National Institute of Heart Diseases/National University of Medical Sciences (NUMS) Pakistan
  • Fasih Ullah Department of Cardiology, Armed forces Institute of Cardiology/National Institute of Heart Diseases/National University of Medical Sciences (NUMS) Pakistan
  • Atif Ghafoor Department of Cardiology, Armed forces Institute of Cardiology/National Institute of Heart Diseases/National University of Medical Sciences (NUMS) Pakistan

DOI:

https://doi.org/10.51253/pafmj.v75i6.11720

Keywords:

Anterior wall myocardial infarction, coronary angiography, electrocardiogram, left anterior descending artery, ST-elevation myocardial infarction

Abstract

Objective: To assess blockage site in left anterior descending coronary artery by means of Electrocardiogram (ECG).

Study Design: Prospective longitudinal study.

Place and Duration of Study: Armed forces Institute of Cardiology & National Institute of Heart Diseases, Pakistan from Aug to Feb, 2024.

Methodology: This study was conducted on 101 patients with acute anterior wall myocardial infarction (AWMI). Included patients had chest pain in last 12 hours. ECG was done in all patients upon presentation. Localization of occlusion site in LAD territory was identified using pre-specified algorithm. Afterwards, each patient underwent coronary angiography to make sure the findings of ECG for occlusion site in LAD territory. Sensitivity, specificity, positive and negative predictive value and accuracy for ECG patterns were also calculated by taking angiographic findings as gold standard for occlusion site detection.

Results: A total of one hundred and one study participants were comprised of 85(84.2%) male and 16(15.8%) female patients and mean age was 61.87±10.39 years.  Among patients with anterior wall myocardial infarction (AWMI), 28 (27.7%) showed blockage in LAD before origin of both 1st septal(S1) and 1st diagonal(D1) branch. For occlusions before origin of S1 and after D1, after S1 and before D1, and after both S1 and D1, the numbers were 7(6.9%), 8 (7.9%), and 58(57.4%), respectively.

Conclusion: ECG is not only useful in guiding the timely administration of reperfusion therapy but also in offering insights into the severity and site of blockage in individuals diagnosed with AWMI before encountering angiography.

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Published

31-12-2025

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Section

Original Articles

How to Cite

1.
Ishaq Z, Nadeem A, Ahmed N, Ahmed I, Mumtaz Z, Azad N, et al. Electrocardiogram (ECG) Pattern of Left Anterior Descending Coronary Artery Occlusion in Acute Anterior Myocardial Infarction Cases. Pak Armed Forces Med J [Internet]. 2025 Dec. 31 [cited 2026 Jan. 2];75(6):1219-23. Available from: https://pafmj.org/PAFMJ/article/view/11720