Comparison of Corticosteroids Effectiveness via High Volume Nasal Irrigation versus Conventional Nasal Spray after Endoscopic Sinus Surgery in Nasal Polyposi

Chaudhry Muhammad Bilal Akram; Abdul  Hakim; Aftab  Hussain; Muhammad Zubair  Khan; Maryam  Khan; Kamran Ashfaq Ahmed  Butt

doi:10.51253/pafmj.v75i2.11240

Authors

Chaudhry Muhammad Bilal Akram Department of ENT, Combined Military Hospital Kohat/National University of Medical Sciences (NUMS) Pakistan
Abdul Hakim Department of ENT, Combined Military Hospital Multan/National University of Medical Sciences (NUMS) Pakistan
Aftab Hussain Department of Anesthesia, Combined Military Hospital Kohat/National University of Medical Sciences (NUMS) Pakistan
Muhammad Zubair Khan Department of ENT, Khyber Medical University Institute of Medical Sciences, Kohat Pakistan
Maryam Khan Department of ENT, RHQ Hospital, Skardu Pakistan
Kamran Ashfaq Ahmed Butt Department of ENT, Combined Military Hospital Kohat/National University of Medical Sciences (NUMS) Pakistan

DOI:

https://doi.org/10.51253/pafmj.v75i2.11240

Keywords:

Corticosteroids, Corticosteroid Irrigation, Endoscopic Sinus Surgery, FESS, Nasal Polyposis, Recurrent Nasal Polyposis.

Abstract

Objective: To compare the efficacy of two different methods of topical corticosteroid delivery techniques; conventional nasal spray versus high volume nasal irrigation with squeeze bottle, post-operatively in patients of nasal polyposis.

Study Design: Quasi-experimental study.

Place and Duration of Study: Department of Ear Nose Throat, Combined Military Hospital, Kohat Pakistan, from Sep 2021 to Aug 2022.

Methodology: A total of 80 patients diagnosed with nasal polyposis were recruited for this study. Selected patients were divided into two equal groups. Pre-operatively all patients were carefully assessed with the help of Sino-nasal outcome test 22 (SNOT 22) and Lund Kennedy Endoscopy score for severity of symptoms. Post-operatively, Group-A received Betamethasone via high volume irrigation by squeeze bottle whereas Group-B received the Beclomethasone via conventional nasal spray. This treatment plan continued for 3 months. Post-operatively, SNOT 22 and Lund Kennedy Endoscopy score assessment was carried out at 3 months.

Results: Both groups were comparable with respect to demographic data. In Group-A pre-op median and interquartile range for SNOT score was 68 and 10 respectively and it was reduced to 14 and 5 post-operatively, whereas in Group-B, it was 68 and 10; 27 and 5.5 pre and post-operatively. Post-operative difference was significant (p-value=0.001). Similarly, in Group-A, pre and post-operative median and interquartile range for LKE score 6 and 1 respectively and 2 and 0, whereas in Group-B it was 6.22 and 0.4 and 1.5 with statistically significant post-operative difference (p-value=0.001).

Conclusion: High volume irrigation with squeeze bottle is more effective method of delivering....

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