Frequency of Subclinical Hypothyroidsim Among Patients with end Stage Renal Disease on Hemodialysis Presenting to A Tertiary Care Hospital

Authors

  • Wajid Abdullah Department of Medicine, Niazi Medical & Dental College, Sargodha Pakistan
  • Salman Tahir Shafi Department of Medicine, Akhtar Saeed Medical College, Rawalpindi Pakistan
  • Irfan Ahmad Department of Medicine, Sharif Medical City Hospital, Lahore Pakistan
  • Sana Ashraf Department of Pediatric, Indus Hospital, Raiwind Lahore Pakistan

DOI:

https://doi.org/10.51253/pafmj.v73i5.11155

Keywords:

Chronic kidney disease, End stage renal disease, Subclinical hypothyroidism

Abstract

Objective: Aim of this study was to determine the frequency of subclinical hypothyroidism among patients with end stage
renal disease presenting to tertiary care hospital.

Study Design: Cross sectional study.

Place and Duration of Study: Department of Nephrology, Sharif Medical City Hospital, Lahore. Pakistan, from Mar 2020 to
Dec 2020.

Methodology: A total of 200 cases studied. Informed consent was obtained from them. Data was noted in the proforma.
Using aseptic techniques blood sample was taken for testing serum TSH and free T4 levels through radioimmunoassay.
Results were collected by the researcher next day and were labeled and noted as subclinical hypothyroidism according to its
clinical definition. Privacy of the data was maintained.

Results: In 200 study cases age interval was 15-80 years with mean age of 46.22±19.67 years. The minimum Serum TSH
level was 4.1 and maximum was 4.6 with mean serum TSH level was 4.31±0.16. The minimum Serum T4 levels was 0.5 and
maximum was 2.1 with mean Serum T4 levels was 1.28±0.68. Duration of chronic kidney disease was 3-60 months with mean
duration of 17.58±14.14 months. It was observed that there were 56.5% male patients while females were 43.5%. Subclinical
Hypothyroidism was present in 9.5% patients with ESRD reporting to tertiary care hospital while it was absent in 90.5%
patients.

Conclusion: The frequency of subclinical hypothyroidism was found as 9.5% among patients with end stage renal disease
presenting to tertiary care hospital.

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Published

30-10-2023

Issue

Section

Original Articles

How to Cite

1.
Wajid Abdullah, Salman Tahir Shafi, Irfan Ahmad, Sana Ashraf. Frequency of Subclinical Hypothyroidsim Among Patients with end Stage Renal Disease on Hemodialysis Presenting to A Tertiary Care Hospital. Pak Armed Forces Med J [Internet]. 2023 Oct. 30 [cited 2024 Jul. 25];73(5):1484-7. Available from: https://pafmj.org/PAFMJ/article/view/11155