A Study of Anti Microbial Resistance  in Salmonella Enterica Serovars Typhi and Paratyphi A At CMH  Quetta

Haseeb Nasir; Hassan Shabbir; Nadia Tayyab; Sayed Tanveer Abbas; Maryam Zafar

doi:10.51253/pafmj.v75iSUPPL-1.11059

Authors

Haseeb Nasir Department of Medicine, Combined Military Hospital Quetta/ National University of Medical Sciences (NUMS) Pakistan
Hassan Shabbir Department of Medicine, Combined Military Hospital Quetta/ National University of Medical Sciences (NUMS) Pakistan
Nadia Tayyab Department of Pathologist, Combined Military Hospital Quetta /National University of Medical Sciences (NUMS) Pakistan
Sayed Tanveer Abbas Department of Pathologist, Combined Military Hospital Quetta /National University of Medical Sciences (NUMS) Pakistan
Maryam Zafar Department of Radiology, Combined Military Hospital Quetta /National University of Medical Sciences (NUMS) Pakistan

DOI:

https://doi.org/10.51253/pafmj.v75iSUPPL-1.11059

Keywords:

Antibiotic Reistances, Enteric fever, salmonella enterica typhi, and salmonella enterica paratyphi

Abstract

Objectives: To ascertain the antimicrobial resistance of Paratyphi A and Typhi Serovars of Salmonella Enterica

Study Design: Prospective Observational Study

Place and Duration of Study: Clinical Microbiology Laboratory at the CMH Quetta November 2022-Septmeber 2023

Patients and

Methodology: The data from the lab were reviewed in this investigation Blood cultures from 1441 admitted patients from the Medicine department supplied to the laboratory of the CMH Quetta between November 2022 and September 2023 were tested for antibiotic susceptibility and Typhoidal Salmonellae were isolated.

Results: Out of total 1441 isolates, 839(58.2%) were isolates of Salmonela Typhi and 602(41.8%) were S Paratyphi .These microbes had maximum resistance against Ceftriaxone (71.6%, 67.2%), Ciprofloxacin (70.6%, 66.6%). S typhi and paratyphi have minimal resistance to Meropenum 7.7% and 9.13% respectively. These patients had maximum sensitivity for Meropenum.

Conclusion: S. Typhi and S. Paratyphi have high rates of multidrug resistance against Ceftriaxone and Ciprofloxacin. Meropenum had found to have minimal resistance.

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