Assessment of Left Ventricular Systolic and Diastolic Functions on Echocardiography in Cirrhotic Patients

Abstract

Objective: To assess the prevalence of left ventricular (LV) systolic and diastolic function on Echocardiography (ECHO) in
patients presented with liver cirrhosis.

Study Design: Analytical Cross-sectional study.

Place and Duration of Study: Armed Forces Institute of Cardiology/National Institute of Heart Diseases Rawalpindi,
Pakistan, from Apr 2023 to May 2023.

Methodology: Total of n=131 liver cirrhotic patients were recruited by non-probability consecutive sampling technique. All
these patients presented and diagnosed with liver cirrhosis on ultrasound, were selected. Their echocardiographic assessment was done by an experienced operator. Gathered data specially the LV diastolic and systolic function, was entered and analyzed in SPSS version-24:00. Chi-square and analysis of variance was applied to find the p-values for study variables in relation with severity of liver cirrhosis. p-value <0.05 was taken statistically significant.

Results: Out of 131 Patients, 85(64.9%) patients had liver cirrhosis for less than 5-years, 32(24.4%) had for 5-10 years and
14(10.68%) for more than 10-years. There was almost similar frequency of males and females [67(51.1%) and 64(48.9%)
respectively] with mean age of 57.14±9.84 years. Statistically significant association of demographics and clinical parameters with liver cirrhosis was found (p<0.05) except left ventricular systolic diameter (p>0.05). LV diastolic dysfunction was reported in 94(71.8%) while systolic function was normal in all participants. LV diastolic dysfunction was found in 56(42.7%) as grade-I, 31(23.7%) as grade-II and 7(5.3%) cases as grade-III which was statistically significant (p<0.001).

Conclusion: Diastolic dysfunction is relatively more common in liver cirrhosis patients as compared to systolic function. There was significant ...