Comparison of Post-Operative Surgical Site Infection in Uncomplicated Laparoscopic Cholecystectomies in Patients Who Received Post-Operative Antibiotics versus Patients who did not Receive Post-Operative Antibiotics; A Comparative Study
DOI:
https://doi.org/10.51253/pafmj.v75i1.10358Keywords:
Laparoscopic Cholecystectomy, Post-operative Antibiotics, Surgical Site Infection.Abstract
Objective: To compare the frequency of post-op “surgical site infection” in uncomplicated laparoscopic cholecystectomies in patients who received post-op antibiotics versus those who did not.
Study Design: Quasi-experimental study
Place and Duration of Study: Department of General Surgery, Combined Military Hospital, Rawalpindi, Pakistan from Jun 2022 to May 2023.
Methodology: A total of 342 patients [171 in the Antibiotics-Group and 171 in the No-Antibiotics-Group] fulfilling the inclusion criteria who underwent uneventful laparoscopic cholecystectomy were included in the study. In all these patients, baseline characteristics were documented. Patients in Group-A were given antibiotic therapy post-operatively, while patients in Group-B were not given antibiotics after the operation. Patients in both groups were followed up on day 10 after the surgery to assess for “surgical site infection.
Results: In our study, the mean age of the study population was 38.41±10.12 years. There were 127(37.13%) male participants, while 215(62.87%) participants were female. The mean body mass index (BMI) was 31.14±4.49 kg/m2. Composite frequency of “surgical site infection” was 38(11.10%). In patients who were given post-op antibiotics, the frequency of “surgical site infection” was 16(9.35%), while in patients who did not receive any antibiotics after the surgery, the frequency of “surgical site infection” was 22(12.86%), (p=0.302).
Conclusion: Antibiotic therapy should be reserved for patients who develop “surgical site infection” instead of being used in all patients.
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Copyright (c) 2025 Umer Naeem, Syed Mukarram Hussain, Muhammad Danial Yousaf, Muhammad Saqlain, Muhammad Imran, Najm Ul Hassan
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