Comparison of Post-Operative Surgical Site Infection in Uncomplicated Laparoscopic Cholecystectomies in Patients Who Received Post-Operative Antibiotics versus Patients who  did not Receive Post-Operative Antibiotics; A Comparative Study

Authors

  • Umer Naeem Department of General Surgery, Combined Military Hospital/National University of Medical Sciences (NUMS) Rawalpindi Pakistan
  • Syed Mukarram Hussain Department of General Surgery, Combined Military Hospital/National University of Medical Sciences (NUMS) Rawalpindi Pakistan
  • Muhammad Danial Yousaf Department of General Surgery, Combined Military Hospital/National University of Medical Sciences (NUMS) Rawalpindi Pakistan
  • Muhammad Saqlain Department of General Surgery, Combined Military Hospital/National University of Medical Sciences (NUMS) Rawalpindi Pakistan
  • Muhammad Imran Department of General Surgery, Combined Military Hospital/National University of Medical Sciences (NUMS) Rawalpindi Pakistan
  • Najm Ul Hassan Department of General Surgery, Combined Military Hospital/National University of Medical Sciences (NUMS) Rawalpindi Pakistan

DOI:

https://doi.org/10.51253/pafmj.v75i1.10358

Keywords:

Laparoscopic Cholecystectomy, Post-operative Antibiotics, Surgical Site Infection.

Abstract

Objective: To compare the frequency of post-op “surgical site infection” in uncomplicated laparoscopic cholecystectomies in patients who received post-op antibiotics versus those who did not.

Study Design: Quasi-experimental study

Place and Duration of Study: Department of General Surgery, Combined Military Hospital, Rawalpindi, Pakistan from Jun 2022 to May 2023.

Methodology: A total of 342 patients [171 in the Antibiotics-Group and 171 in the No-Antibiotics-Group] fulfilling the inclusion criteria who underwent uneventful laparoscopic cholecystectomy were included in the study. In all these patients, baseline characteristics were documented. Patients in Group-A were given antibiotic therapy post-operatively, while patients in Group­-B were not given antibiotics after the operation. Patients in both groups were followed up on day 10 after the surgery to assess for “surgical site infection.

Results: In our study, the mean age of the study population was 38.41±10.12 years. There were 127(37.13%) male participants, while 215(62.87%) participants were female. The mean body mass index (BMI) was 31.14±4.49 kg/m2. Composite frequency of “surgical site infection” was 38(11.10%). In patients who were given post-op antibiotics, the frequency of “surgical site infection” was 16(9.35%), while in patients who did not receive any antibiotics after the surgery, the frequency of “surgical site infection” was 22(12.86%), (p=0.302).

Conclusion: Antibiotic therapy should be reserved for patients who develop “surgical site infection” instead of being used in all patients.

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References

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Published

28-02-2025

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Original Articles

How to Cite

1.
Naeem U, Hussain SM, Yousaf MD, Saqlain M, Imran M, Hassan NU. Comparison of Post-Operative Surgical Site Infection in Uncomplicated Laparoscopic Cholecystectomies in Patients Who Received Post-Operative Antibiotics versus Patients who  did not Receive Post-Operative Antibiotics; A Comparative Study. Pak Armed Forces Med J [Internet]. 2025 Feb. 28 [cited 2025 Mar. 28];75(1):68-72. Available from: https://pafmj.org/PAFMJ/article/view/10358