Dyslipidaemia In Acute Non-Cardioembolic Ischemic Stroke Patients At A Tertiary Care Center


  • Muhammad Umair Department of Medicine, National University of Medical Sciences (NUMS) Pakistan
  • Asad Zaman Khan Department of Medicine, National University of Medical Sciences (NUMS) Pakistan
  • Asad Bilal Mir Department of Surgery, National University of Medical Sciences (NUMS) Pakistan
  • Muhammad Farrukh Habib Department of Public Health, National University of Medical Sciences (NUMS) Pakistan
  • Iqra Iqbal Department of Medicine, DHQ Teaching Hospital Gujranwala Pakistan
  • Jamshaid Iqbal Department of Medicine, National University of Medical Sciences (NUMS) Pakistan




Cardio-embolic ischemic stroke, Dyslipidaemia, Lipid, Lipoprotein


Objective: To determine the frequency of dyslipidaemia in acute non-cardio embolic ischemic stroke patients at a tertiary care centre in Rawalpindi.

Study Design: Cross-sectional study

Place and Duration of Study: Neurology Department, Pak Emirates Military Hospital (PEMH), Rawalpindi Pakistan, Jul 2022
to Feb 2023.

Methodology: Patients with acute non-cardio embolic ischemic stroke were included. Data was collected from the patient files and hospital records including a thorough history, physical examination information, CT/MRI brain, fasting lipid profiles
with total cholesterol (TC), low-density lipoprotein cholesterol (LDL-C), high-density lipoprotein cholesterol (HDL-C), and
triglycerides (TG).

Results: The study included 196 patients, of which dyslipidaemia was seen with a major share of high TG in 44(22.44%),
followed by high LDL cholesterol in 38(19.38%), and high TC was found in 28(14.28%).

Conclusion: More than 1/3rd of patients with acute non-cardioembolic ischemic stroke have dyslipidaemia.


Download data is not yet available.


Metrics Loading ...


Coupland AP, Thapar A, Qureshi MI, Jenkins H, Davies AH.

The definition of stroke. J R Soc Med 2017; 110(1): 9-12.


Shah SP, Shrestha A, Pandey SR, Sigdel K, Sah N, Panthi S, et al.

Dyslipidemia in Acute Non-cardioembolic Ischemic Stroke

Patients at a Tertiary Care Centre: A Descriptive Cross-sectional

Study. J Nepal Med Assoc 2022; 60(247): 241-245.


Siddeswari R, Manohar S, Sudarsi B, Suryanarayana B, Kumar

SP, Abhilash T. Pattern of dyslipidemia in ischemic stroke. J

Med Allied Sci 2015; 5(2): 26-29.

Pearson GJ, Thanassoulis G, Anderson TJ, Barry AR, Couture P,

Dayan N, et al. 2021 Canadian Cardiovascular Society

Guidelines for the Management of Dyslipidemia for the

Prevention of Cardiovascular Disease in Adults. Can J Cardiol

; 37(8): 1129-1150.


Klijn CJ, Hankey GJ; American Stroke Association and European

Stroke Initiative. Management of acute ischaemic stroke: new

guidelines from the American Stroke Association and European

Stroke Initiative. Lancet Neurol. 2003; 2(11): 698-701.


Yang LP, Keating GM. Fenofibric acid: in combination therapy

in the treatment of mixed dyslipidemia. Am J Cardiovasc Drugs

; 9(6): 401-409.


Xing XY, Li GW, Yao CH, Rao KQ, Kong LZ; Technical Working

Group of China National Nutrition and Health Survey. [The

association of stroke with high plasma low-density lipoprotein

cholesterol level and metabolic syndrome in Chinese adults].

Zhonghua Nei Ke Za Zhi 2009; 48(5): 388-391.

Scheitz JF, MacIsaac RL, Abdul-Rahim AH, Siegerink B, Bath

PM, Endres M, et al; VISTA collaboration. Statins and risk of

poststroke hemorrhagic complications. Neurology 2016; 86(17):

-1596. https://doi.org/10.1212/WNL.0000000000002606

Teh WL, Abdin E, Vaingankar JA, Seow E, Sagayadevan V,

Shafie S, et al. Prevalence of stroke, risk factors, disability and

care needs in older adults in Singapore: results from the WiSE

study. BMJ Open 2018; 8(3): e020285.


Kulshrestha M, Vidyanand. An analysis of the risk factors and

the outcomes of cerebrovascular diseases in northern India. J

Clin Diagn Res 2013; 7(1): 127-131.


Maskey A, Parajuli M, Kohli SC. A study of risk factors of stroke

in patients admitted in Manipal Teaching Hospital, Pokhara.

Kathmandu Uni Med J 2011; 9(4): 244-247.

Expert Panel on Detection, Evaluation, and Treatment of High

Blood Cholesterol in Adults. Executive Summary of The Third

Report of The National Cholesterol Education Program (NCEP)

Expert Panel on Detection, Evaluation, And Treatment of High

Blood Cholesterol In Adults (Adult Treatment Panel III). JAMA

; 285(19): 2486-2497.


Zhuo Y, Wu J, Qu Y, Yu H, Huang X, Zee B, et al. Clinical risk

factors associated with recurrence of ischemic stroke within two

years: A cohort study. Medicine 2020; 99(26): e20830.


Kumar R, Lakhair MA, Memon Z. Ischemic Stroke: Frequency of

Dyslipidemia and Other Risk Factors at Tertiary Care Hospital

Hyderabad/Jamshoro. The Professional Med J 2016; 23(08): 925-

Khan MN, Khan HD, Ahmad M, Umar M. Serum total and

HDL-cholesterol in ischemic and hemorrhagic stroke. Ann Pak

Inst Med Sci 2014; 10(1): 22-26.

Olamoyegun MA, Akinlade AT, Fawale MB, Ogbera AO.

Dyslipidaemia as a risk factor in the occurrence of stroke in

Nigeria: prevalence and patterns. Pan Afr Med J 2016; 25: 72.


Park JH, Lee J, Ovbiagele B. Nontraditional serum lipid

variables and recurrent stroke risk. Stroke 2014; 45(11): 3269-


Curb JD, Abbott RD, Rodriguez BL, Masaki KH, Chen R, Popper

JS, Petrovitch H, Ross GW, Schatz IJ, Belleau GC, Yano K. High

density lipoprotein cholesterol and the risk of stroke in elderly

men: the Honolulu heart program. Am J Epidemiol 2004; 160(2):

-157. https://doi.org/10.1093/aje/kwh177

Kurth T, Everett BM, Buring JE, Kase CS, Ridker PM, Gaziano

JM. Lipid levels and the risk of ischemic stroke in women.

Neurology 2007; 68(8): 556-62.





How to Cite

Umair, M., Khan, A. Z., Mir, A. B., Habib, M. F., Iqbal, I., & Iqbal, J. (2024). Dyslipidaemia In Acute Non-Cardioembolic Ischemic Stroke Patients At A Tertiary Care Center. Pakistan Armed Forces Medical Journal, 74(1), 202–205. https://doi.org/10.51253/pafmj.v74i1.10337



Original Articles

Most read articles by the same author(s)

1 2 > >>