Diagnostic Value of Hyperbilirubinemia as a Predictor for Appendiceal Perforation in Acute Appendicitis
DOI:
https://doi.org/10.51253/pafmj.v75iSUPPL-4.10166Keywords:
Appendicitis, Appendectomy, Bilirubin, Diagnostic Accuracy, Perforation.Abstract
Objectives: To determine the diagnostic accuracy of hyperbilirubinemia as a predictor for “appendiceal perforation” in acute appendicitis.
Study Design: validation study.
Place and Duration of Study: Department of General Surgery, Combined Military Hospital, Rawalpindi Pakistan, from Sep to Feb 2022.
Methodology: A total of 96 patients having acute appendicitis were included Serum bilirubin levels were documented. Patients then underwent appendectomy and based on operative finding diagnosis of simple/perforated appendicitis was made. 2x2 table was drawn for sensitivity, specificity, PPV and NPV.
Results: In our study, mean age of study population was 20.86±3.26 years. There 46(47.90%) male participants while remaining 50(52.10%) participants were female. Mean duration of symptoms was 10.79±2.56 hours. Mean serum bilirubin was 1.28±0.74 mg/dl. Sensitivity, specificity, positive predictive value and negative predictive value of “hyperbilirubinemia” as a predictor for “appendiceal perforation” in acute appendicitis was 63.64%, 76.92%, 70.00% and 71.43%, respectively.
Conclusion: Raised serum levels of bilirubin can serve as a potentially useful laboratory test for predicting “appendiceal perforation”.
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Copyright (c) 2025 Sohaib Ashraf, Muhammad Shoaib Khan, Paras Ibn E Ali, Sajid Ali, Rashid Iqbal Khan, Abdur Rehman Rashid
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