Off-Label Fortified Antibiotic Therapy as a Standard Regimen for Infective Ophthalmic Pathologies and Real-Time Challenges

Authors

  • Taimoor Ashraf Khan Department of Ophthalmology, Armed Forces Institute of Ophthalmology/National University of Medical Sciences (NUMS), Rawalpindi Pakistan
  • Abdul Rauf Department of Ophthalmology, Armed Forces Institute of Ophthalmology/National University of Medical Sciences (NUMS), Rawalpindi Pakistan
  • Saad Hassan Bhatti Department of Ophthalmology, Armed Forces Institute of Ophthalmology/National University of Medical Sciences (NUMS), Rawalpindi Pakistan
  • Teyyeb Azeem Janjua Department of Ophthalmology, Armed Forces Institute of Ophthalmology/National University of Medical Sciences (NUMS), Rawalpindi Pakistan
  • Muhammad Shahid Department of Ophthalmology, Armed Forces Institute of Ophthalmology/National University of Medical Sciences (NUMS), Rawalpindi Pakistan
  • Muhammad Ahsan Mukhtar Department of Ophthalmology, Armed Forces Institute of Ophthalmology/National University of Medical Sciences (NUMS), Rawalpindi Pakistan

DOI:

https://doi.org/10.51253/pafmj.v73iSUPPL-2.9355

Keywords:

Antibiotic resistance, Climate change, Fortified antibiotics, Infective ocular pathologies, Superbugs, Topical drug waste

Abstract

 

Over time fortified antibiotics have become the therapy of choice for sight-threatening infective ocular pathologies as
compared to commercially available low-concentration antibiotics. However, there are multiple challenges to their use. These
include preparation under inadequate clinical settings with improperly trained staff, non-availability of designated vehicle
systems and storing medicine at extremes of temperatures - facilities for which are not available everywhere. Furthermore,
cost of these fortified antibiotics, poor patient compliance and an increased risk of infection question their main stream use.
Lastly, an ever-growing problem of the rise of "superbugs" as a result of the injudicious use of these antibiotics along with
unnecessary drug waste which contributes to climate change raises question regarding their long-term viability and necessity
for treating sight-threatening ocular pathologies

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Published

25-07-2023

Issue

Section

Review Articles

How to Cite

1.
Khan TA, Rauf A, Bhatti SH, Janjua TA, Shahid M, Mukhtar MA. Off-Label Fortified Antibiotic Therapy as a Standard Regimen for Infective Ophthalmic Pathologies and Real-Time Challenges. Pak Armed Forces Med J [Internet]. 2023 Jul. 25 [cited 2024 Jun. 14];73(SUPPL-2):S398-400. Available from: https://pafmj.org/PAFMJ/article/view/9355