Acute Kidney Injury in Neonates who Develop Asphyxia at the Time of Delivery

Authors

  • Saba Zamir Department of Pediatrics, Pak Emirates Military Hospital/National University of Medical Sciences (NUMS) Rawalpindi Pakistan
  • Muhammad Tariq Nadeem Department of Pediatrics, Pak Emirates Military Hospital/National University of Medical Sciences (NUMS) Rawalpindi Pakistan
  • Lutfullah Goheer Department of Pediatrics, Combined Military Hospital, Multan/National University of Medical Sciences (NUMS) Pakistan

DOI:

https://doi.org/10.51253/pafmj.v73i4.8988

Keywords:

Acute kidney injury, Birth asphyxia, Infant mortality

Abstract

Objective: To determine the frequency of acute kidney injury in neonates who develop asphyxia at delivery.

Study Design: Cross-sectional study.

Place and Duration of Study: Department of Paediatrics, Pak-Emirates Military Hospital, Rawalpindi Pakistan, Aug 2021 to Feb 2022.

Methodology: This study was based on 69 patients diagnosed with birth asphyxia on the basis of APGAR score at 5 minutes. Patients underwent testing for serum creatinine levels at 24 hours post-delivery, as well as the monitoring of urine output, and acute kidney injury was classified according to the KDIGO classification, based on the increase in serum creatinine levels and urine output.

Results: Acute kidney injury was observed in 12(17.4%) cases and 3(4.3%) neonates died. Lower gestational age at birth was associated with acute kidney injury (p=0.038), and acute kidney injury was associated with a higher chance for mortality (p<0.001). Additionally, male infants had a lower head circumference (p=0.001), a lower total body length (p<0.001) and a lower APGAR score at birth (p=0.004) when compared to females. However, they did not appear to have a higher risk for acute kidney injury (p=0.121).

Conclusion: Acute kidney injury following the development of birth asphyxia is a common occurrence in our population efforts should be made to identify pregnancies at risk to mitigate this potentially devastating complication.

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Published

31-08-2023

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Original Articles

How to Cite

1.
Zamir S, Nadeem MT, Goheer L. Acute Kidney Injury in Neonates who Develop Asphyxia at the Time of Delivery. Pak Armed Forces Med J [Internet]. 2023 Aug. 31 [cited 2024 Jul. 25];73(4):1165-8. Available from: https://pafmj.org/PAFMJ/article/view/8988