EFFICACY OF 5% POTASSIUM HYDROXIDE VERSUS 10% POTASSIUM HYDROXIDE SOLUTION FOR THE TREATMENT OF MOLLUSCUM CONTAGIOSUM AT A TERTIARY CARE HOSPITAL

  • Hina Saleem Baloch Pakistan Naval Ship Hospital, Shifa Karachi Pakistan
  • Najia Ahmed Pakistan Naval Ship Hospital, Shifa Karachi Pakistan
  • Arfan Ul Bari Pakistan Naval Ship Hospital, Shifa Karachi Pakistan
  • Omer Farooq Pakistan Naval Ship Hospital, Shifa Karachi Pakistan
  • Abdullah Ahmad Waqar Qureshi Aster Clinic, Dubai
Keywords: Efficacy, Molluscum contagiosum, Potassium hydroxide (KOH), Safety

Abstract

Objective: To compare the efficacy of 5% potassium hydroxide (KOH) and 10% potassium hydroxide (KOH) solution for the treatment of molluscum contagiosum at a tertiary care Hospital.

Study Design: Quasi-experimental study.

Place and Duration of Study: Dermatology Department, Tertiary Care Hospital Karachi, from Oct 2019 to Apr 2021.

Methodology: Sixty patients with molluscum contagiosum who fulfilled the inclusion and exclusion criteria were enrolled in the outpatient department of tertiary care hospital in Karachi. Patients were divided into two groups, A (5% KOH) and B (10% KOH) of 30 patients each. Potassium Hydroxide (KOH) solution was applied at home using the cotton-tipped applicator twice daily. Follow-up of patients was done at 2-weekly intervals for 12 weeks. Efficacy was measured based on the resolution of lesions or improvement from baseline.

Results: Complete response occurred in 23 (76.7%) cases in 10% KOH Group while 6 (20%) in 5% KOH Group, Partial response occurred in 6 (20%) in 10% KOH group while 15 (50%) in 5% KOH group, No response occurred in 1 (3.33%) in 10% KOH group and 9 (30%) in 5% KOH group (p<0.001).

Conclusion: 10% Potassium Hydroxide (KOH) is an efficient modality for the treatment of molluscum contagiosum compared to 5% Potassium Hydroxide (KOH).

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Published
2021-12-31
How to Cite
Baloch, H., Ahmed, N., Bari, A., Farooq, O., & Qureshi, A. A. (2021). EFFICACY OF 5% POTASSIUM HYDROXIDE VERSUS 10% POTASSIUM HYDROXIDE SOLUTION FOR THE TREATMENT OF MOLLUSCUM CONTAGIOSUM AT A TERTIARY CARE HOSPITAL. PAFMJ, 71(6), 2135-38. https://doi.org/10.51253/pafmj.v71i6.6807
Section
Original Articles