PROGNOSIS OF INTENSIVE CARE UNIT ACQUIRED HYPERNATREMIA IN DIFFERENT AGE GROUPS AND GENDER

Abstract

Objective: To find out the frequency of intensive care unit acquired hypernatremia in critically ill patients and to find out the outcomes in terms of mortality/discharge with respect to age and gender.

Study Design: Cross sectional study.

Place and Duration of Study: Medical, trauma and surgical intensive care unit settings of Combined Military Hospital Kohat, from Jun 2018 to Jun 2019.

Methodology: A total of 100 patients were enrolled who were normonatremic at the time of intensive care unit admission. Patients were followed for 2 weeks of their stay for intensive care unit acquired complications and mortality. Serum sodium levels along with other investigations were carried out on daily basis from a single pathology laboratory. Data including the clinical diagnosis, APACHE II score and intensive care unit acquired complications was recorded on a proforma. Data was analyzed using SPSS version 22 and Microsoft Excel 365.

Results: The frequency of intensive care unit acquired hypernatremia was 46 (46%) further classified into mild 13 (13%), moderate 15 (15%) and severe 18 (18%) hypernatremia. The overall mortality was 30 (30%), 10 (18.5%) and 20 (43.5%) cases in normal and raised serum sodium group respectively. We reported a slightly higher frequency of Intensive care unit acquired hypernatremia in our study. The mortality was also significant in hyponatremic group.

Conclusion: Intensive care unit acquired hypernatremia was an invaluable marker for quality health care in critically ill patients and it’s also an important risk factor for Intensive care unit associated mortality.