FREQUENCY OF PEDIATRIC BRAIN TUMORS IN TERTIARY CARE INSTITUTE OF PAKISTAN AND COMPARISON WITH INTERNATIONAL DATA

  • Muhammad Owais Qurni Armed Forces Institute of Pathology/National University of Medical Sciences (NUMS) Rawalpindi Pakistan
  • Hassan Tariq Armed Forces Institute of Pathology/National University of Medical Sciences (NUMS) Rawalpindi Pakistan
  • Hiba Tahir Federal Medical & Dental College, Islamabad Pakistan
  • Hafeez Ud Din Armed Forces Institute of Pathology/National University of Medical Sciences (NUMS) Rawalpindi Pakistan
  • Hamza Mansur Armed Forces Institute of Pathology/National University of Medical Sciences (NUMS) Rawalpindi Pakistan
  • Maria Nadeem Armed Forces Institute of Pathology/National University of Medical Sciences (NUMS) Rawalpindi Pakistan
Keywords: Brain tumor, Pilocytic Astrocytoma, Glioma, Ependymoma, Pediatric

Abstract

Objective: To analyze the histological spectrum of pediatric brain tumors (PBT) in Pakistani population and to compare the results with international data.

Study Design: Retrospective observational study.

Place and Duration of Study: Armed Forces Institute of Pathology, Rawalpindi, from Jan 2015 and Dec 2019.

Methodology: This data was analyzed using the latest World Health Organization (WHO) classification of Tumors of Central Nervous System 2016. The cases were divided in 5 categories according to age (0-2, 3-5, 6-8, 9-11 & 12-14 years).

Results: A total of 43 cases were included in the study. Of these cases, 26 (60.46%) were male and 17 (39.5%) were female. Male to female ratio was 1.5-1. The 6-8 year age group had the highest number of tumors while 0-2 year age group had the least. Mean age of diagnosis was 7.6 years. Ependymoma wasthe most common morphological type with 12 cases (28%) followed by pilocytic astrocytoma, diffuse glioma with 10 cases each (23%) and medulloblastoma with 9 cases (21%). Least common tumor subtype was Ewing sarcoma. Ependymoma were mostly of grade 3 (64%), pilocytic astrocytoma and medulloblastoma were of grade 1 and grade 4 respectively by definition, and diffuse gliomas were mainly of grade 2 (57%) type.

Conclusion: Ependymoma and pilocytic astrocytomaare the most frequent types of pediatric brain tumors in our region which follows the same trend as mentioned in western and regional literature.

Downloads

Download data is not yet available.
Published
2021-06-30
How to Cite
Qurni, M., Tariq, H., Tahir, H., Din, H., Mansur, H., & Nadeem, M. (2021). FREQUENCY OF PEDIATRIC BRAIN TUMORS IN TERTIARY CARE INSTITUTE OF PAKISTAN AND COMPARISON WITH INTERNATIONAL DATA. PAFMJ, 71(3), 989-92. https://doi.org/10.51253/pafmj.v71i3.5479
Section
Original Articles

Most read articles by the same author(s)