VERTICAL TRANSMISSION OF CORONA VIRUS DISEASE-19 (COVID-19) FROM INFECTED PREGNANT MOTHERS TO NEONATES

  • Abeera Choudry Pak Emirates Military Hospital/National University of Medical Sciences (NUMS) Rawalpindi Pakistan
  • Jehan Ara Rafiq Baig Pak Emirates Military Hospital/National University of Medical Sciences (NUMS) Rawalpindi Pakistan
  • Zainab Abbas Mirza Pak Emirates Military Hospital/National University of Medical Sciences (NUMS) Rawalpindi Pakistan
  • Munawar Jannat Pak Emirates Military Hospital/National University of Medical Sciences (NUMS) Rawalpindi Pakistan
  • Zeeshan Ahmed Pak Emirates Military Hospital/National University of Medical Sciences (NUMS) Rawalpindi Pakistan
  • Mobeen Shafique Pak Emirates Military Hospital/National University of Medical Sciences (NUMS) Rawalpindi Pakistan
Keywords: Corona Virus Disease-19 (COVID-19) vertical transmission, Immunoglobulins, Pregnancy, Reverse transcriptase polymerase chain reaction (RT-PCR)

Abstract

Objective: To assess the vertical transmission of Corona Virus disease (COVID-19) from infected pregnant mothers to neonates.

Study Design: Cross sectional study.

Place and Duration of Study: Department of Obstetrics and Gynaecology, Pak Emirates Military Hospital Rawalpindi, from May 2020 to Jun 2020.

Methodology: A total of 90 pregnant patients reported in Pak Emirates Military Hospital during the pandemic of COVID-19 with COVID-19 test positive from 01 May 2020 to 30 June 2020. Diagnosis was confirmed with reverse transcriptase polymerase chain reaction (RT- PCR) of nasal and throat swabs. Clinical, analytical, laboratory and radiographic findings were then recorded. The (RT-PCR) for COVID-19 of all the babies who were delivered to these mothers was also done on throat and nasal swabs. The neonatal blood was also sent for serology (IgM/IgG).

Results: Out of 90 patients studied, 46 were delivered either through a Caesarean section or by vaginal delivery. The patients were categorized as asymptomatic 51 (55.66%) and symptomatic 39 (43.33%). Out of those symptomatic, patients with mild to moderate disease were 33 (84.61%), patients with severe disease 05 (12.82%) and critically ill patient was 01 (2.56%). All the patients who delivered were COVID-19 test positive at the time of delivery and later when the babies of all these mothers were tested, they were all found to be COVID-19 negative on RT-PCR and no immunoglobulins were found in the serum of these neonates. The possibility for transplacental transmission could only be checked by these two methods (RT-PCR and Serology) since RT-PCR of.............

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Published
2020-09-02
How to Cite
Choudry, A., Baig, J., Mirza, Z., Jannat, M., Ahmed, Z., & Shafique, M. (2020). VERTICAL TRANSMISSION OF CORONA VIRUS DISEASE-19 (COVID-19) FROM INFECTED PREGNANT MOTHERS TO NEONATES. PAFMJ, 70(2), S444-49. Retrieved from https://pafmj.org/index.php/PAFMJ/article/view/5225
Section
Original Articles

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