COMPARISON OF EFFECT OF SILICON OIL ON CENTRAL CORNEAL THICKNESS AND CORNEAL ENDOTHELIAL-CELL DENSITY

Changes in Central Cornial Thickness And Corneal Endothelial-Cell Density

Authors

  • Mohammad Asim Mehboob Pakistan Naval Ship (PNS) Shifa Hospital Karachi Pakistan
  • Qamar Ul Islam Pakistan Naval Ship (PNS) Shifa Hospital Karachi Pakistan
  • Ahsan Mukhtar Armed Forces Institute of Ophthalmology (AFIO)/ National University of Medical Sciences (NUMS) Rawalpindi Pakistan
  • Mazhar Ishaq Armed Forces Institute of Ophthalmology (AFIO)/ National University of Medical Sciences (NUMS) Rawalpindi Pakistan

Keywords:

Central corneal thickness, Corneal endothelial-cell density, Removal of silicon oil.

Abstract

Objective: To compare the mean changes in central corneal thickness (CCT) and corneal endothelial-cell density (CED) after removal of silicon oil (ROSO) using anterior (limbal) versus posterior (pars plana) approach in aphakic patients following successful retinal re attachment surgery.
Study Design: Randomized controlled trial.
Place and Duration of Study: Armed Forces Institute of Ophthalmology (AFIO) Rawalpindi, from Dec 2014 to Aug 2015.
Material and Methods: Sixty eyes of 60 aphakic patients who underwent removal of silicon oil from December 2014 to August 2015 in AFIO after successful retinal re-attachment surgery were analysed. Thirty eyes underwent removal of silicon oil through anterior (limbal) approach (group1) and 30 eyes through posterior (pars plana) approach (group-2). Pre-operative central corneal thickness and corneal endothelial-cell density was measured and compared with central corneal thickness and corneal endothelial-cell density measurements 3 months after removal of silicon oil.
Results: Mean age of study population was 49.93 ± 5.18 years. Both groups were age and sex matched (p=0.694 and p=0.80 respectively). In group 1, mean change in CCT was 1.80 ± 6.58 micro meters (μm) and mean change in CED was 196.30 ± 33.78 cells per millimetres square (mm2), while in group 2, mean change in CCT was 1.63 ± 8.96 μm and mean change in CED was 60.20 ± 39.75 cells/mm2 after 3 months of ROSO. Mean change in CCT between two groups was not statistically significant (p=0.935), however, mean change in CED between two groups was statistically significant (p<0.001).
Conclusion: Removal of silicon oil through anterior (limbal) approach causes significant reduction in CED, as compared to posterior (pars plana) approach in aphakic patients following successful retinal reattachment surgery.

 

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Published

30-06-2017

How to Cite

Mehboob, M. A., Ul Islam, Q., Mukhtar, A., & Ishaq, M. (2017). COMPARISON OF EFFECT OF SILICON OIL ON CENTRAL CORNEAL THICKNESS AND CORNEAL ENDOTHELIAL-CELL DENSITY: Changes in Central Cornial Thickness And Corneal Endothelial-Cell Density. Pakistan Armed Forces Medical Journal, 67(3), 391–96. Retrieved from https://pafmj.org/PAFMJ/article/view/485

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