FREQUENCY OF HELICOBACTER PYLORI IN HISTOLOGICALLY PROVEN GASTRITIS CASES - A STUDY OF 100 CASES
Helicobacter Pylori in Gastritis
Objective: To determine the frequency of Helicobacter pylori (H. pylori) based on endoscopic biopsy with the help of special stains in gastritis cases.
Study Design: Prospective descriptive study.
Place and Duration of Study: Histopathology department, Army Medical College Rawalpindi, from Oct 2016 to Mar 2017.
Material and Methods: One hundred (100) cases were included in the study. Gastric biopsies of the patients histologically diagnosed as gastritis were included in the study, which were evaluated for the presence of H. pylori with the help of special stain (Modified Giemsa stain).
Results: Gastric biopsies of 100 patients, who were diagnosed as gastritis on histopathological examination were analyzed with the help of Giemsa stain for the presence or absence of H. pylori. Out of these 100 cases, 60 were males and 35 were females. Most patients were between the age group of 30-40 years. Histological examination and special stain analysis revealed presence of H. pylori in 30 cases (30%), while rest of the 70 cases (70%) showed no H. pylori. Out of 30 cases positive for H. pylori, 28 cases (93%) had chronic active gastritis, while 2 cases (7%) had no element of activity.
Conclusion: Among the cases of chronic gastritis, H. pylori negative gastritis was more common than H. pylori associated gastritis. A significantly decreased frequency of H. pylori in histologically gastritis cases in our population may be due to more frequent use of complete or incomplete therapies against H. pylori by general practitioners at some stage of disease.